Ultrasound therapeutic apparatus using a therapeutic ultrasonic

57 Pages·2013·3.07 MB·English

US005984881A
United States Patent [19] [11] Patent Number: 5,984,881
Ishibashi et al. [45] Date of Patent: Nov. 16, 1999
[54] ULTRASOUND THERAPEUTIC APPARATUS 5,111,822 5/1992 Dory .
USING A THERAPEUTIC ULTRASONIC 5,143,073 9/1992 Dory .
WAVE SOURCE AND AN ULTRASONIC 5,150,712 9/1992 Dory .
PROBE 5,391,140 2/1995 Shaetzke et al. ......................... .. 601/4
5,431,621 7/1995 Dory ......................................... .. 601/2
[75] Inventors: Yoshiharu Ishibashi, Tokyo; 5,435,311 7/1995 Umemura et al. ............... .. 128/66003
Katsuhiko Fujimoto, UraWa; Mariko 5,558,092 9/1996 Unger et al ...................... .. 128/66003
Shibata, Yokohama; Takuji Suzuki,
FOREIGN PATENT DOCUMENTS
Kawasaki; Satoshi Aida, Tokyo, all of
Japan 0 162 735 11/1985 European Pat. Off. .
0 170 416 2/1986 European Pat. Off. .
[73] Assignee: Kabushiki Kaisha Toshiba, Kawasaki, 0 370 841 3/1990 European Pat. Off. .
Japan 0 627 206 12/1994 European Pat. Off. .
42 27 800 3/1993 Germany .
42 29 817 3/1994 Germany .
[21] Appl. No.: 08/624,104 43 02 538 4/1994 Germany .
6-59289 8/1994 Japan .
[22] Filed: Mar. 29, 1996
[30] Foreign Application Priority Data Primary Examiner—George Manuel
Attorney, Agent, or Firm—Oblon, Spivak, McClelland,
Mar. 31, 1995 [JP] Japan .................................. .. 7-097474 Maier & Neustadt P C
Aug. 9, 1995 [JP] Japan .................................. .. 7-203576 ’ ' '
[51] Int. Cl.6 ..................................................... .. A61H 1/00 [57] ABSTRACT
[52] US. Cl. ................................................................. .. 601/2 An ultrasonic therapeutic apparatus consisting of a thera
[58] Field of Search ..................... .. 601/2, 3, 4; 600/449, peutic ultrasonic Wave generating source driven by a driver
600/459 circuit to generate therapeutic ultrasonic Waves, an in vivo
imaging probe so as to obtain a tissue tomographic image in
[56] References Cited the vicinity of the focus of the therapeutic ultrasonic Waves.
U'S' PATENT DOCUMENTS The imaging probe is used to receive echoes of the ultrasonic
pulses emitted from therapeutic ultrasonic Wave generating
Re. 33,590 5/1991 Dory . source. The driving conditions for the therapeutic ultrasonic
4,617,931 10/1986 Dory . Wave generating source is adjusted on the basis of a received
4,620,546 11/1986 Aida et a1- - echo signal. The received echo signal contains information
4,658,828 4/1987 DOTY- about actual intensity of the therapeutic ultrasonic Waves
479427878 7/1990 Dofy ' Within a living body, thus improving the safety and reliabil
4,986,275 1/1991 Ishida et al. . it of thera
5,076,277 12/1991 IWama et al. .................... .. 128/66003 y W‘
5,080,101 1/1992 Dory .
5,080,102 1/1992 Dory . 6 Claims, 35 Drawing Sheets
CONSOLE
40~ ULTRASONIC DIAGNOSTIC C I
SECTION I0
FREGUENCY- INFORMATION -\_ 4‘ {a
ANALYZER /
ROINTE‘TNG
I6 '\~ ~ 43 ULTRASONIC 5 |GNAL
THERAPY SECTION GENERATOR
J
46(II 5) SYSTEM
2 ’ CONTROLER
I
\ CALCULATING
/ SECTION
\\ 42 // S
5 \ / 4 44 45
\\ // (
6 \ ’ MEMORY S
\ / 9
U.S. Patent Nov. 16,1999 Sheet 1 0f35 5,984,881
CONSOLE
WCAONV E I Nuous NH
GENERATING
+5 14 CIRCUIT
\ \ c T
MATCHING _ B PULSE ‘_ *
CIRCUIT ‘ RF AMP , w GENERATOR
1 SYNCH—
3 “2 RONIZING
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{6 TRANS_ GENERATOR 5
T \ MITTING °
\ CIRCUIT E
( Z
2 s 18 8
4 {7 2O 2
\\ // S E
\ / >
5 \\ / m
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6 \ / DELAY
/g, - _{> CIRCUIT
3 9x
22
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8m1QESSlNG
ECHO
FILTER
/ &
PULSE DOPPLER
UNIT DS'C ‘J
S 28/
27
F- CRT
I G- * 29w O
U.S. Patent Nov. 16,1999 Sheet 2 0f35 5,984,881
CRT
RECEIVING \
DELAY SYSTEM CONTROLER 9
CIRCUIT 2o 29~<>
ECHO FILTERl 22
21\ f
3}’ HIGH- K 32H
FREQUENCY ~
HPF ) \ PROCESSING 03C
cmcun 28 N,
3:
LOW
» LPF FREQUENCY
PROCESSING
CIRCUIT "32L
~27
PULSE DOPPLER
UNIT
FIG. 2
F I G. 3 FOCUS
U.S. Patent 5,984,881
Nov. 16, 1999 Sheet 3 0f 35
/
SECOND SYNC
SIGNAL
4
ULTRASONIC PULSE TIME
FOR
IMAGING
"FIRST SYNC SIGNAL
TIME
ULTRASONIC PULSE
FOR INTENSITY
\DISTRIBUTION IMAGING
F I 6.4
9,4
H I GH- FREQUENCY
PULSE GENERATI NG
SW-2 RF-AMP 1 CIRCUIT
11111; I34
SW-I
35 C
B I C CONTINUOUS WAVE 18
I
H IGH GENERATING CIRCUIT I
FREQUENCY SYNCH- <
SW-I
MC RON I Z I NG
IGNAL
GENERATOR SCOYNSTRTOELEMR
TRANSMITTING
IRECEIVING
CIRCUIT
DSC

U.S. Patent Nov. 16,1999 Sheet 5 0f35 5,984,881
RECIEVED 51* 5F 523
SIGNAL FR
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INIAGING
EQUALIZER —SPECTRUM
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F l G. T (DS-C)
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WAVE BAND (240) (3 f0)
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'f\ -\ / SPECTRUM 0F
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FIG. 8
U.S. Patent Nov. 16,1999 Sheet 6 0f35 5,984,881
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U.S. Patent Nov. 16,1999 Sheet 7 0f35 5,984,881
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SHIFT BAND BY BLOOD STREAM
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RECIEVED SIGNAL
FIG. H
U.S. Patent Nov. 16,1999 Sheet 9 0f35 5,984,881
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