The renal drug handbook: the ultimate prescribing guide for renal practitioners

1037 Pages·2019·4.613 MB·English

by  Ashley, Caroline, Dunleavey, Aileen

The Renal Drug Handbook
The ultimate prescribing guide
for renal practitioners
FOURTH EDITION
Edited by
Caroline Ashley and Aileen Dunleavy
UK Renal Pharmacy Group
Foreword by
Professor David C Wheeler
Professor of Kidney Medicine
University College London
President, Renal Association
Boca Raton London New York
CRC Press is an imprint of the
Taylor & Francis Group, an informa business
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
© 2014 Caroline Ashley and Aileen Dunleavy
CRC Press is an imprint of Taylor & Francis Group, an Informa business
No claim to original U.S. Government works
Printed on acid-free paper
Version Date: 20140214
International Standard Book Number-13: 978-1-9093-6894-1 (Hardback)
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Contents
Foreword to the fourth edition xii
Preface to the fourth edition xiii
About the editors xvii
List of abbreviations xviii
Abacavir 1 Amifostine 41
Abatacept 2 Amikacin 42
Abciximab 3 Amiloride hydrochloride 44
Abiraterone acetate 4 Aminophylline 45
Acamprosate calcium 5 Amiodarone hydrochloride 47
Acarbose 6 Amisulpride 49
Acebutolol 7 Amitriptyline hydrochloride 51
Aceclofenac 9 Amlodipine 53
Acenocoumarol (nicoumalone) 10 Amoxicillin 54
Acetazolamide 12 Amphotericin IV – Abelcet (lipid complex) 55
Acetylcysteine 13 Amphotericin IV – AmBisome (liposomal) 57
Aciclovir IV 14 Amphotericin IV – Fungizone 59
Aciclovir oral 16 Ampicillin 61
Acipimox 17 Amsacrine 62
Acitretin 18 Anagrelide 63
Acrivastine 19 Anakinra 64
Adalimumab 20 Anastrozole 65
Adefovir dipivoxil 21 Anidulafungin 66
Adenosine 22 Apixaban 67
Adrenaline (epinephrine) 23 Apomorphine hydrochloride 68
Albendazole (unlicensed product) 24 Aprepitant 69
Aldesleukin 25 Argatroban 70
Alemtuzumab (MabCampath) (unlicensed) 26 Aripiprazole 72
Alendronic acid 27 Arsenic trioxide 74
Alfacalcidol 28 Artemether with lumefantrine 76
Alfentanil 29 Ascorbic acid 77
Alfuzosin hydrochloride 31 Asenapine 78
Alimemazine tartrate (trimeprazine) 32 Aspirin 79
Aliskiren fumarate 33 Atazanavir 81
Allopurinol 34 Atenolol 83
Almotriptan 35 ATG (Rabbit) (Thymoglobuline) 85
Alteplase (rt-PA) (recombinant human Atorvastatin 87
tissue-type plasminogen activator) 36 Atovaquone 89
Aluminium hydroxide 38 Atracurium besilate 90
Amantadine hydrochloride 39 Axitinib 91
Ambrisentan 40 Azacitidine 92
iv CONTENTS
Azathioprine 93 Capecitabine 146
Azilsartan medoxomil 95 Capreomycin 147
Azithromycin 96 Captopril 148
Aztreonam 98 Carbamazepine 150
Carbimazole 152
Baclofen 99 Carboplatin 153
Balsalazide sodium 100 Carmustine 154
Basiliximab 101 Carvedilol 155
Belatacept 102 Caspofungin 157
Belimumab 103 Cefaclor 158
Bendamustine hydrochloride 104 Cefadroxil 159
Bendrofl umethiazide 105 Cefalexin 160
Benzbromarone (unlicensed product) 107 Cefi xime 161
Benzylpenicillin 108 Cefotaxime 162
Betahistine dihydrochloride 109 Cefpodoxime 163
Betamethasone 110 Cefradine 164
Betaxolol hydrochloride 111 Ceftaroline 165
Bevacizumab 112 Ceftazidime 166
Bexarotene 113 Ceftriaxone 167
Bezafi brate 114 Cefuroxime (oral) 168
Bicalutamide 115 Cefuroxime (parenteral) 169
Bilastine 116 Celecoxib 170
Bisacodyl 117 Celiprolol hydrochloride 172
Bisoprolol fumarate 118 Certolizumab pegol 173
Bivalirudin 119 Cetirizine hydrochloride 174
Bleomycin 120 Cetuximab 175
Boceprevir 122 Chloral hydrate 176
Bortezomib 124 Chlorambucil 177
Bosentan 125 Chloramphenicol 178
Brentuximab vedotin 127 Chlordiazepoxide hydrochloride 179
Bromocriptine 128 Chloroquine 180
Budesonide 129 Chlorphenamine maleate
Bumetanide 130 (chlorpheniramine) 182
Buprenorphine 132 Chlorpromazine hydrochloride 183
Bupropion hydrochloride Chlortalidone (chlorthalidone) 185
(amfebutamone HCL) 133 Ciclosporin 187
Buserelin 134 Cidofovir 189
Buspirone hydrochloride 135 Cilazapril 191
Busulfan 136 Cilostazol 192
Cimetidine 194
Cabazitaxel 137 Cinacalcet 196
Cabergoline 138 Cinnarizine 197
Calcitonin (salmon)/salcatonin 139 Ciprofi brate 198
Calcitriol 140 Ciprofl oxacin 199
Calcium acetate 141 Cisplatin 201
Calcium carbonate 142 Citalopram 203
Calcium gluconate 143 Cladribine 205
Calcium resonium 144 Clarithromycin 206
Candesartan cilexetil 145 Clemastine 208
CONTENTS v
Clindamycin 209 Decitabine 268
Clobazam 210 Deferasirox 269
Clofazimine 211 Deferiprone 270
Clomethiazole (chlormethiazole) 212 Defl azacort 271
Clomipramine hydrochloride 213 Degarelix 272
Clonazepam 215 Demeclocycline hydrochloride 273
Clonidine hydrochloride 216 Denosumab 274
Clopidogrel 217 Desferrioxamine mesilate 275
Clozapine 218 Desirudin (unlicensed product) 277
Co-amoxiclav (amoxicillin/clavulanic acid) 220 Desloratadine 278
Co-beneldopa (Madopar) 222 Desmopressin (DDAVP) 279
Co-careldopa (Sinemet) 223 Dexamethasone 280
Co-codamol (paracetamol and codeine Dexibuprofen 282
phosphate) 224 Dexketoprofen 284
Codeine phosphate 226 Diamorphine hydrochloride 286
Co-dydramol (paracetamol and Diazepam 287
dihydrocodeine) 227 Diazoxide 289
Colchicine 228 Diclofenac sodium 290
Colesevelam hydrochloride 230 Didanosine 292
Colestipol hydrochloride 231 Digoxin 293
Colestyramine (cholestyramine) 232 Dihydrocodeine tartrate 295
Colistimethate sodium (Colistin) 233 Diltiazem hydrochloride 296
Co-trimoxazole (trimethoprim + Dipyridamole 298
sulfamethoxazole) 235 Disodium etidronate 299
Crisantaspase 237 Disodium pamidronate 300
Crizotinib 238 Disopyramide 301
Cyclizine 240 Disulfi ram 303
Cyclopenthiazide 241 Dobutamine 304
Cyclophosphamide 242 Docetaxel 305
Cycloserine 244 Domperidone 306
Cyproheptadine hydrochloride 245 Donepezil hydrochloride 307
Cyproterone acetate 246 Dopamine hydrochloride 308
Cytarabine 247 Dopexamine hydrochloride 309
Cytomegalovirus (CMV) human Doripenem 310
immunoglobulin (unlicensed product) 249 Dornase alfa 311
Dosulepin hydrochloride (dothiepin) 312
Dabigatran etexilate 250 Doxapram hydrochloride 314
Dacarbazine 252 Doxazosin 315
Dactinomycin 253 Doxepin 316
Dalteparin sodium (LMWH) 254 Doxorubicin hydrochloride 318
Danaparoid sodium 256 Doxycycline 320
Dapaglifl ozin 258 Dronedarone 321
Dapsone 259 Droperidol 323
Daptomycin 260 Duloxetine 325
Darbepoetin alfa 262 Dutasteride 326
Darifenacin 264
Darunavir 265 Eculizumab 327
Dasatinib 266 Efavirenz 328
Daunorubicin 267 Eletriptan 330
vi CONTENTS
Eltrombopag 332 Fesoterodine fumarate 398
Emtricitabine 334 Fexofenadine hydrochloride 399
Enalapril maleate 335 Fidaxomicin 400
Enfuvirtide 337 Filgrastim 401
Enoxaparin sodium (LMWH) 338 Finasteride 402
Entacapone 340 Fingolimod 403
Entecavir 341 Flecainide acetate 404
Epirubicin hydrochloride 342 Flucloxacillin 406
Eplerenone 344 Fluconazole 407
Epoetin alfa (Eprex) 346 Flucytosine 409
Epoetin beta (Neorecormon) 348 Fludarabine phosphate 410
Epoprostenol (prostacyclin) 350 Fludrocortisone acetate 411
Eprosartan 351 Flumazenil 412
Eptifi batide 352 Fluorouracil 413
Eribulin 353 Fluoxetine 414
Erlotinib 354 Flupentixol 416
Ertapenem 356 Flurbiprofen 417
Erythromycin 357 Flutamide 419
Escitalopram 359 Fluvastatin 420
Eslicarbazepine acetate 361 Fluvoxamine maleate 421
Esmolol hydrochloride 362 Folic acid 423
Esomeprazole 364 Folinic acid (calcium folinate) 424
Estramustine phosphate 366 Fondaparinux sodium 425
Etamsylate 367 Formoterol fumarate (eformoterol) 427
Etanercept 368 Fosamprenavir 428
Ethambutol hydrochloride 369 Fosaprepitant 430
Ethosuximide 370 Foscarnet sodium 431
Etodolac 371 Fosfomycin (unlicensed) 433
Etomidate 373 Fosinopril sodium 434
Etoposide 374 Fosphenytoin sodium 435
Etoricoxib 376 Frovatriptan 437
Etravirine 378 Fulvestrant 438
Everolimus 379 Furosemide (frusemide) 439
Exemestane 380
Exenatide 381 Gabapentin 441
Ezetimibe 382 Galantamine 442
Ganciclovir 443
Famciclovir 383 Gefi tinib 445
Famotidine 384 Gemcitabine 446
Febuxostat 385 Gemfi brozil 448
Felodipine 387 Gentamicin 450
Fenofi brate 388 Glatiramer acetate 451
Fenoprofen 389 Glibenclamide 452
Fentanyl 391 Gliclazide 453
Ferric carboxymaltose 393 Glimepiride 454
Ferrous fumarate 394 Glipizide 455
Ferrous gluconate 395 Glyceryl trinitrate 456
Ferrous sulphate 396 Goserelin 457
Ferumoxytol 397 Granisetron 458
CONTENTS vii
Griseofulvin 459 Ketamine 523
Guanethidine monosulphate 460 Ketoconazole 525
Ketoprofen 527
Haloperidol 461 Ketorolac trometamol 529
Heparin 463 Ketotifen 531
Hydralazine hydrochloride 464 Klean-Prep 532
Hydrocortisone acetate 465
Hydrocortisone sodium succinate 466 Labetalol hydrochloride 533
Hydromorphone hydrochloride 468 Lacidipine 535
Hydroxycarbamide (hydroxyurea) 469 Lacosamide 536
Hydroxychloroquine sulphate 470 Lactulose 537
Hydroxyzine hydrochloride 472 Lamivudine 538
Hyoscine butylbromide 473 Lamotrigine 539
Hyoscine hydrobromide 474 Lanreotide 541
Lansoprazole 542
Ibandronic acid 475 Lanthanum carbonate 543
Ibuprofen 477 Lapatinib 544
Idarubicin hydrochloride 479 Lefl unomide 545
Ifosfamide 481 Lenalidomide 546
Iloprost 483 Lenograstim 547
Imatinib 484 Lercanidipine hydrochloride 548
Imidapril hydrochloride 486 Letrozole 549
Imipramine hydrochloride 487 Leuprorelin acetate 550
Indapamide 489 Levamisole (unlicensed product) 551
Indinavir 491 Levetiracetam 552
Indometacin 493 Levocetirizine hydrochloride 553
Indoramin 495 Levofl oxacin 554
Infl iximab 496 Levomepromazine (methotrimeprazine) 555
Inositol nicotinate 497 Levothyroxine sodium (thyroxine) 557
Insulin – soluble (Actrapid or Humulin S) 498 Lidocaine hydrochloride (Lignocaine) 558
Interferon alfa-2a (Roferon A) 499 Linagliptin 560
Interferon alfa-2b 501 Linezolid 561
Interferon beta 503 Liothyronine sodium (triiodothyronine) 563
Interferon gamma-1b (Immukin) 504 Liraglutide 564
Ipilimumab 505 Lisinopril 565
Ipratropium bromide 506 Lithium carbonate 566
Irbesartan 507 Lofepramine 568
Irinotecan hydrochloride 508 Lomitapide 570
Iron dextran 5% solution 510 Lomustine 571
Iron isomaltoside 1000 512 Loperamide hydrochloride 572
Iron sucrose 513 Lopinavir 573
Isoniazid 514 Loratadine 575
Isosorbide dinitrate 515 Lorazepam 576
Isosorbide mononitrate 516 Lormetazepam 577
Isotretinoin 517 Losartan potassium 578
Ispaghula husk 518 Lymecycline 579
Isradipine 519
Itraconazole 520 Maraviroc 580
Ivabradine hydrochloride 522 Mebendazole 581
viii CONTENTS
Medroxyprogesterone acetate 582 Moxifl oxacin 642
Mefenamic acid 584 Moxisylyte (thymoxamine) 643
Mefl oquine 586 Moxonidine 644
Megestrol acetate 587 Muromonab CD3 (OKT3) (unlicensed) 645
Melatonin 588 Mycophenolate 646
Meloxicam 589
Melphalan 591 Nabumetone 648
Memantine 593 Nadolol 650
Mepacrine hydrochloride (unlicensed Naftidrofuryl oxalate 652
product) 594 Nalidixic acid 653
Meptazinol 595 Nalmefene hydrochloride dihydrate 654
Mercaptopurine 596 Naloxone hydrochloride 655
Meropenem 598 Naltrexone hydrochloride 656
Mesalazine 599 Naproxen 657
Mesna 600 Naratriptan 659
Metformin hydrochloride 601 Natalizumab 660
Methadone hydrochloride 602 Nateglinide 661
Methenamine hippurate 604 Nebivolol 662
Methotrexate 605 Nefopam hydrochloride 664
Methyldopa 607 Nelarabine 665
Methylprednisolone 608 Neomycin sulphate 666
Metoclopramide hydrochloride 609 Neostigmine 667
Metolazone (unlicensed) 610 Nevirapine 668
Metoprolol tartrate 612 Nicardipine hydrochloride 670
Metronidazole 614 Nicorandil 671
Mexiletine hydrochloride (unlicensed) 615 Nicotinic acid (unlicensed) 672
Micafungin 617 Nifedipine 673
Miconazole 618 Nilotinib 675
Midazolam 619 Nimodipine 676
Midodrine hydrochloride (unlicensed) 621 Nitrazepam 678
Mifamurtide 622 Nitrofurantoin 679
Minocycline 623 Nizatidine 680
Minoxidil 624 Noradrenaline acid tartrate
Mirabegron 625 (norepinephrine bitartrate) 681
Mircera 626 Norethisterone 682
Mirtazapine 627 Norfl oxacin 683
Misoprostol 628 Normal human immunoglobulin 684
Mitomycin 629 Nortriptyline 686
Mitotane 630 Nystatin 688
Mitoxantrone 631
Mivacurium 632 Octreotide 689
Mizolastine 634 Oestrogen, conjugated (unlicensed
Moclobemide 635 product) 690
Modafi nil 636 Ofatumumab 691
Moexipril hydrochloride 637 Ofl oxacin 692
Montelukast 638 Olanzapine 693
Morphine 639 Olmesartan medoxomil 694
Movicol (active ingredient is the Olsalazine sodium 695
osmotic laxative polyethylene glycol) 641 Omalizumab 696
CONTENTS ix
Omeprazole 697 Piperazine 754
Ondansetron 698 Piracetam 755
Orlistat 699 Piroxicam 756
Orphenadrine hydrochloride 700 Pivmecillinam hydrochloride 758
Oseltamivir 701 Pizotifen 759
Oxaliplatin 703 Plerixafor 760
Oxazepam 705 Posaconazole 761
Oxcarbazepine 706 Potassium chloride 763
Oxprenolol hydrochloride 707 Pramipexole 764
Oxybutynin hydrochloride 709 Prasugrel 765
Oxycodone hydrochloride 710 Pravastatin sodium 766
Oxytetracycline 711 Praziquantel (unlicensed product) 767
Prazosin 768
Paclitaxel 712 Prednisolone 769
Paliperidone 713 Pregabalin 770
Palonosetron 714 Primaquine phosphate 771
Pancreatin 715 Primaxin (imipenem/cilastatin) 772
Pancuronium bromide 716 Primidone 774
Panitumumab 717 Procainamide hydrochloride
Pantoprazole 718 (unlicensed) 776
Papaveretum 719 Procarbazine 778
Paracetamol 720 Prochlorperazine 779
Parathyroid hormone 721 Procyclidine hydrochloride 781
Parecoxib 722 Proguanil hydrochloride 782
Paricalcitol 724 Promazine hydrochloride 783
Paroxetine 725 Promethazine hydrochloride 784
Pazopanib 727 Propafenone hydrochloride 785
Pegfi lgrastim 728 Propiverine hydrochloride 787
Peginterferon alfa 729 Propofol 788
Pemetrexed 730 Propranolol hydrochloride 789
Penicillamine 731 Propylthiouracil 791
Pentamidine isetionate 732 Protamine sulphate 792
Pentostatin 734 Pseudoephedrine hydrochloride 793
Pentoxifylline (oxpentifylline) 735 Pyrazinamide (unlicensed product) 794
Perampanel 736 Pyridostigmine bromide 795
Perindopril 737 Pyridoxine hydrochloride 796
Pethidine hydrochloride 739 Pyrimethamine 797
Phenelzine 740
Phenindione 741 Quetiapine 798
Phenobarbital (phenobarbitone) 742 Quinagolide 800
Phenoxybenzamine hydrochloride 744 Quinapril 801
Phenoxymethylpenicillin (penicillin V) 745 Quinine 802
Phentolamine mesilate 746
Phenytoin 747 Rabeprazole sodium 804
Phosphate supplements 749 Racecadotril 805
Phytomenadione (vitamin K) 750 Raloxifene hydrochloride 806
Pimozide 751 Raltegravir 807
Pindolol 752 Raltitrexed 808
Pioglitazone 753 Ramipril 809