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The Dynamic Neuron PDF

163 Pages·2002·0.811 MB·English
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by John Smythies| 2002| 163 pages| 0.811| English

About The Dynamic Neuron

The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity.The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease.

Detailed Information

Author:John Smythies
Publication Year:2002
ISBN:9780262194730
Pages:163
Language:English
File Size:0.811
Format:PDF
Price:FREE
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