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QSAR and Drug Design: New Developments and Applications PDF

509 Pages·1995·19.121 MB·English
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by Toshio Fujita| 1995| 509 pages| 19.121| English

About QSAR and Drug Design: New Developments and Applications

Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline. They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octano/water) for compound series of medicinal-chemical interest are analyzed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach. A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.

Detailed Information

Author:Toshio Fujita
Publication Year:1995
Pages:509
Language:English
File Size:19.121
Format:PDF
Price:FREE
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