Table Of ContentPRATEEK SHARMA, MD, FACP, FACG
Division of Gastroenterology and Hepatology
University of Kansas School of Medicine
VA Medical Center
Kansas City, MO
Certifications
Diplomate of American Board of Gastroenterology
ECFMG certified
FLEX certified
License to practice medicine - Kansas
License to practice medicine - Missouri
Academic Appointments & Clinical Experience
Professor Gastroenterology & Hepatology
Of Medicine: University of Kansas School of Medicine
VA Medical Center, Kansas City, MO
May 2007-present
Program Fellowship, Gastroenterology & Hepatology
Director: University of Kansas School of Medicine
May 2002-present
Section Gastroenterology & Hepatology
Chief: VA Medical Center, Kansas City, MO
October 2004-present
Associate Gastroenterology & Hepatology
Professor University of Kansas School of Medicine
of Medicine: VA Medical Center, Kansas City, MO
May 2002-April 2007
Assistant Gastroenterology & Hepatology
Professor University of Kansas School of Medicine
of Medicine: VA Medical Center, Kansas City, MO
October 1998-April 2002
Fellowship: Gastroenterology
University of Arizona, Tucson AZ
July 1995-June 1998
University of Kansas, Kansas City, KS
July 1998-September 1998
Residency: Internal Medicine
1
Medical College of Wisconsin, Milwaukee,
WI
July 1993-June 1995
Internship: Internal Medicine
Christ Hospital & Medical Center, Oak
Lawn, IL
July 1992-June 1993
Education
Graduate Education: MB, BS Bachelor of Medicine & Bachelor of
Surgery
MS University of Baroda, India (1986-1991)
Graduated as the Valedictorian
Peer Review Publications
1. Sharma P, Sampliner RE, Camargo E. Normalization of
esophageal pH with high dose proton pump inhibitor therapy
does not result in regression of Barrett’s esophagus. Am J
Gastroenterol 1997;92:582-585.
2. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner
RE. Dysplasia in short segment Barrett’s esophagus – a
prospective three year follow-up. Am J Gastroenterol
1997;92:2012-2106.
3. Sharma P, Jaffe P, Bhattacharyya A. Metastatic
cholangiocarcinoma presenting as ovarian cancer: a rare
Krukenberg tumor. Am J Gastroenterol 1997;92:531-533.
4. Sharma P, Morales TG, Sampliner RE. Short segment Barrett's
esophagus: the need for standardization of the definition and of
endoscopic criteria. Am J Gastroenterol 1998;93:1033-6.
5. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner
RE. Squamous islands in Barrett’s esophagus: what lies
underneath? Am J Gastroenterol 1998;93:332-335.
6. Sharma P, Jaffe PE, Bhattacharyya A, Sampliner RE.
Laser and multipolar electrocoagulation ablation of early
Barrett’s adenocarcinoma: long term follow-up.
Gastrointest Endosc 1999;49:442-6.
7. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner
RE. Durability of new squamous epithelium following endoscopic
reversal of Barrett’s esophagus. Gastrointest Endosc
1999;50:159-64.
8. Garewal HS, Sharma P, Ramsey L, et al. Biomarker
studies in reversed Barrett’s esophagus. Am J
Gastroenterol 1999;94:2829-33.
9. Sharma P, Weston AP, Morales T, Topalovski M, et al. Relative
risk of dysplasia for patients with intestinal metaplasia in the distal
oesophagus and in the gastric cardia. Gut 2000;46:9-13.
2
10.Sharma P, Topalovski M, Mayo M, et al. H pylori eradication
dramatically improves gastric carditis. Am J Gastroenterol
2000;95:3107-3111.
11.Sharma VK, Corder FA, Raufman JP, Sharma P, Fennerty MB,
Howden CW. A survey of
Internal Medicine residents’ use of the fecal occult blood test
and their understanding of colorectal cancer screening. Am J
Gastroenterol 2000;95:2068-73.
12.Weston AP, Sharma P, Topalovski M, et al. Long term follow up
of Barrett’s high grade dysplasia. Am J Gastroenterol
2000;95:1888-1893.
13.Weston AP, Banerjee SK, Sharma P, et al. P53 protein
overexpression positivity in low grade dysplasia in Barrett’s
esophagus: immunohistochemical marker predictive of
progression. Am J Gastroenterol 2001;96:1355-1362.
14.Jones TF, Sharma P, Daaboul B, Cherian R, Mayo M, Topalovski
M, Weston AP. Yield of intestinal metaplasia in patients with
suspected short segment-Barrett’s esophagus (SSBE) on repeat
endoscopy. Dig Dis Sci 2002;47:2108-11.
15.Sharma P, Mayo M, Topalovski M, Weston AP. Methylene blue
chromoendoscopy for the detection of patients with short
segment Barrett’s esophagus. Gastrointest Endosc
2001;54:289-93.
16.Schmitz R, Sharma P, Qamar MJ, et al. Incidence of esophageal
stricture formation, ulcer bleeding, perforation and massive
hematoma formation from sclerotherapy versus banding ligation.
Am J Gastroenterol 2001;96:437-441
17.da Silva VD, Prolla JC, Sharma P, et al. Karyometry in Barrett’s
esophagus. Analytical & Quantitative Cytology & Histology
2001;23:40-46.
18.Sharma P. Short segment Barrett’s esophagus and specialized
columnar mucosa at the gastroesophageal junction. Mayo Clin
Proc 2001;76:331-334
19.Weston AP, Sharma P. Neodymium: Yttrium-aluminum garnet
contact laser ablation of Barrett’s high-grade dysplasia and
early carcinoma. Am J Gastroenterol 2002;97:2998-3006.
20.Sharma P, Weston AP, Topalovski M, Cherian R, Bhattaacharyya A,
Sampliner RE. Magnification chromoendoscopy for the detection of
intestinal metaplasia and dysplasia in
Barrett’s esophagus. Gut 2003;52:24-27.
21.Sharma P, McQuaid K, Dent J. A critical review of the diagnosis
and management of Barrett’s esophagus – The AGA Chicago
workshop. Gastroenterology 2004;127:310-330.
3
22.Connor MJ, Weston A, Mayo MS, Sharma P. Prevalence of
Barrett’s esopahgus and erosive esophagitis in patients
undergoing upper endoscopy for dyspepsia in a VA
population. Dig Dis Sci 2004;49:920-924.
23.Westhoff BC, Weston A, Cherian R, Sharma P. Development of
Barrett’s esophagus six months after total gastrectomy. Am J
Gastroenterol 2004;99:2271-7.
24.Weston AP, Sharma P, Mathur S, Banerjee S, Jafri AK, Cherian R,
McGregor D,
Hassanein RS, Hall M. Risk stratification of Barrett’s
esophagus: updated prospective multivariate analysis. Am J
Gastroenterol 2004;99:1657-1666.
25.Shaheen NJ, Inadomi JM, Overholt BF, Sharma P. What is the best
management strategy for high grade dysplasia (HGD) in Barrett’s
esophagus? A cost-effectiveness analysis. Gut
2004;53:1736-44.
26.Sharma P, McElhinney C, Topalovski M, Mayo M, McGregor D,
Weston A. Detection of cardia intestinal metaplasia: Do the
biopsy number and location matter? Am J Gastroenterol
2004;99:2424-2428.
27.Westhoff B, Weston A, Brotze S, McElhinney C, Mayo M,
Sharma P. The prevalence of Barrett’s esophagus in patients
with chronic gastro-esophageal reflux disease.
Gastrointest Endosc 2005;61:226-31.
28.Weston AP, Sharma P, Banerjee S, Mitreva D, Mathur S. Visible
endoscopic and histologic changes in the cardia, before and after
complete Barrett’s esophagus ablation.
Gastrointest Endosc 2005;61:515-21.
29.Wani S, Sampliner RE, Weston AP, Mathur S, Hall M, Higbee A,
Sharma P. Lack of predictors of normalization of esophageal acid
exposure in Barrett’s esophagus. Aliment Pharmacol Ther
2005;22:627-633.
30.Sharma P, Falk GW, Weston AP, Reker D, Johnston M,
Sampliner RE. Dysplasia and cancer in a large multicenter
cohort of patients with Barrett’s esophagus. Clin Gastroenterol
Hepatol 2006;4:566-572.
31.Sharma P, Wani S, Weston AP, Bansal A, Hall M, Mathur S,
Prasad A, Sampliner RE. A randomized controlled trial of ablation
of Barrett’s esophagus with multipolar electrocoagulation vs.
argon plasma coagulation in combination with acid suppression:
long term results. Gut 2006;55:1233-1239.
32.Hanna S, Rastogi A, Weston AP, Totta F, Schmitz R, Mathur S,
McGregor D, Cherian R, Sharma P. Detection of Barrett’s
esophagus after endoscopic healing of erosive esophagitis. Am J
Gastroenterol 2006;101:1416-20.
4
33.Sharma P, Bansal A, Mathur S, Wani S, Cherian R, McGregor D,
Higbee A, Hall S, Weston A. The utility of a novel narrow band
imaging endoscopy system in patients with
Barrett’s esophagus. Gastrointest Endosc 2006;64:167-75.
34.Spechler S, Sharma P, Traxler B, Levine D, Falk G. Gastric
and esophageal pH in patients with Barrett’s esophagus
treated with three esomeprazole dosages: a randomized,
double-blind, crossover trial. Am J Gastroenterol
2006;101:1964-71.
35.Cohen H, Moraes-Filho JP, Cafferata ML, Tomasso G, Salis G,
Gonzalez O, Valenzuela J, Sharma P, Malfertheiner P, Armstrong
D, Lundell L, Corti R, Sakai P, Ceconello I, Latin-American GORD
Consensus Group. An evidence-based, Latin-American consensus
on gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol
2006;18(4):349-68.
36.Sharma P, Dent J, Armstrong D, Bergman J, Gossner L,
Hoshihara Y, Jankowski J, Junghard O, Lundell L, Tytgat G,
Vieth M. The development and validation of an endoscopic
grading system for Barrett’s esophagus – the Prague C and
M criteria.
Gastroenterology 2006;131:1392-1399.
37.Sharma P, Marcon N, Wani S, Bansal A, Mathur S, Sampliner R,
Lightdale C. Non biopsy detection of intestinal metaplasia and
dysplasia in Barrett’s esophagus: a prospective multicenter study.
Endoscopy 2006;38(12):1206-1212.
38.Rockey DC, Barish M, Brill JV, Cash BD, Fletcher JG, Sharma P,
Wani S, Wiersema MJ, Peterson LE, Conte J. Standards for
gastroenterologists for performing and interpreting diagnostic
computed tomographic colonography. Gastroenterology
2007;133(3):1005-1024.
39.Sharma P, Wani S, Bansal A, Hall S, Puli S, Mathur S,
Rastogi A. A feasibility trial of narrow band imaging
endoscopy in patients with gastroesophageal reflux disease.
Gastroenterology 2007;133(2):454-64.
40.Wani S, Sharma P. Narrow band imaging in Barrett’s
esophagus. Expert Rev Gastroenterol Hepatol
2007;1(1):53-60.
41.Singh S, Bansal A, Puli S, Wani S, Mathur S, Rastogi A, Sharma P.
Effect of proton pump inhibitor therapy on inflammatory changes in
the gastric cardia (carditis). Dig Dis Sci 2007;52(9):2178-82.
42.Rastogi A, Bansal A, Wani S, Callahan P, McGregor DH, Cherian
R, Sharma P. Narrow-band imaging colonoscopy-a pilot feasibility
study for the detection of polyps and correlation of surface
patterns with polyp histologic diagnosis. Gastrointest Endosc
2008;67(2):280-6.
43.Bansal A, Ulusarac O, Mathur S, Sharma P. Correlation
between narrow band imaging and nonneoplastic gastric
pathology: a pilot feasibility trial. Gastrointest Endosc
2008;67:210-6.
5
44.Rastogi A, Puli S, El-Serag HB, Bansal A, Wani S, Sharma P.
Incidence of esophageal adenocarcinoma in patients with
Barrett’s esophagus and high-grade dysplasia: a meta-analysis.
Gastrointest Endosc 2008;67:394-8.
45.Sharma P, Wani S, Rastogi A, Bansal A, Higbee A, Mathur S,
Esquivel R, Camargo L, Sampliner RE. The diagnostic accuracy of
esophageal capsule endoscopy in patients with gastroesophageal
reflux disease and Barrett’s esophagus: A blinded, prospective
study.
Am J Gastroenterol 2008;103:525-532
46.Wani S, Puli SR, Shaheen NJ, Westhoff B, Slehria S, Wei J,
Bansal A, Rastogi A, Sayana H, Sharma P. Esophageal
adenocarcinoma in Barrett’s esophagus after endoscopic ablative
therapy: a meta-analysis and systematic review. Am J
Gastroenterol 2009;104(2):502-513.
47.Rastogi A, Pondugula K, Bansal A, Wani S, Keighley J, Sugar J,
Callahan P, Sharma P. Recognition of surface mucosal and
vascular patterns of colon polyps using narrow band imaging:
interobserver and intraobserver agreement and prediction of polyp
histology.
Gastrointest Endosc 2009;69:716-22
48.Sharma P, Shaheen NJ, Perez MC, Pilmer BL, Lee M, Atkinson
SN, Peura D. Clinical trials: healing of erosive oesophagitis with
dexlansoprazole MR, a proton pump inhibitor with a novel dual
delayed-release formulation – results from two randomized
controlled studies. Aliment Pharmacol Ther 2009;29(7):731-741
49.Shaheen NJ, Sharma P, Overholt BF, et al.
Radiofrequency ablation in Barrett’s esophagus with
dysplasia. N Engl J Med 2009;360(22):2277-88
50.Herrero LA, Curvers WL, Bansal A, Wani S, Kara M, Schenk E,
Schoon EJ, Lynch CR, Rastogi A, Pondugula K, Weusten B,
Sharma P, Bergman JJ. Zooming in on Barrett oesophagus using
narrow-band imaging: an international observer agreement study.
Eur J Gastroenterol Hepatol 2009;21(9):1068-75
51.Rastogi A, Keighley J, Singh V, Callahan P, Bansal A, Wani S,
Sharma P. High accuracy of narrow band imaging without
magnification for the real-time characterization of polyp histology
and its comparison with high-definition white light colonoscopy: A
prospective study. Am J Gastroenterol 2009;104(10):2422-2430
52.Bansal A, Wani S, Rastogi A, Rastogi K, Goyal A, Hall S, Singh V,
Higbee A, Sharma P. Impact of measurement of esophageal acid
exposure close to the gastroesophageal junction on diagnostic
accuracy and event-symptom correlation: a prospective study
using wireless dual pH monitoring. Am J Gastroenterol
2009;104(12):2918-2925
53.Fiocca R, Mastracci L, Riddell R, Takubo K, Vieth M, Yerian L,
Sharma P, Fernstrom P, Ruth M. Development of consensus
guidelines for the histologic recognition of
6
microscopic esophagitis in patients with gastroesophageal
reflux disease: the Esohisto project. Human Pathology
2010;41(2):223-31
54.Wallace MB, Sharma P, Lightdale C, et al. Preliminary accuracy
and interobserver agreement for the detection of intraepithelial
neoplasia in Barrett’s esophagus with probe-based confocal laser
endomicroscopy. Gastrointest Endosc 2010;72(1):19-24
55.Repici A, Hassan C, Sharma P, et al. Systematic review: the role of
self-expanding plastic stents for benign oesophageal strictures.
Aliment Pharmacol Ther 2010;31(12):1268-75
56.Lee YC, Cook MB, Bhatia S, Chow WH, El-Omar EM, Goto H, Lin
JT, Li YQ, Rhee PL, Sharma P, et al. Interobserver reliability in
the endoscopic diagnosis and grading of
Barrett’s esophagus: an Asian multinational study. Endoscopy
2010;42:699-704
57.Wani S, Mathur SC, Curvers WL, Singh V, Herrero LA, Hall SB,
Ulusarac O, Cherian R, McGregor DH, Bansal A, Rastogi A,
Ahmed B, Singh M, Gaddam S, Ten Kate FJ, Bergman J,
Sharma P. Greater interobserver agreement by endoscopic
mucosal resection than biopsy samples in Barrett’s dysplasia.
Clin Gastroenterol Heptaol
2010;8:783-88
58.Gaddam S, Wani S, Ahmed H, Maddur P, Hall SB, Gupta N, Puli
SR, Higbee A, Rastogi A, Bansal A, Sharma P. The impact of pre-
endoscopy proton pump inhibitor use on the classification of non-
erosive reflux disease and erosive oesophagitis. Aliment
Pharmacol Ther 2010;32(10):1266-74
59.Vahabzadeh A, Rastogi A, Bansal A, Sharma P. Use of a
plastic endoprothesis to successfully treat esophageal
perforation following radiofrequency ablation of Barrett’s
esophagus. Endoscopy 2011;43(1):67-9
60.Gaddam S, Maddur P, Wani S, Gupta N, Singh M, Singh V,
Moloney B, Puli SR, Rastogi A, Bansal A, Sharma P. Risk factors
for nocturnal reflux in a large GERD cohort. J Clin Gastroenterol
2011, May 31
61.Bansal A, Lee IH, Hong X, Anand V, Mathur SC, Gaddam S, Rastogi
A, Wani SB, Gupta N, Visvanathan M, Sharma P, Christenson LK.
Feasibility of MicroRNAs as Biomarkers for
Barrett’s Esophagus Progression: A Pilot Cross-Sectional, Phase
2 Biomarker Study. Am J Gastroenterol 2011;104(6):1055-63
62.Tadiparthi RA, Bansal A, Wani S, Mathur S, Hall SB, Rastogi A,
Higbee A, Gaddam S, Sharma P. Dilated intercellular spaces
and lymphocytes on biopsy relate to symptoms in erosive GERD
but not NERD. Aliment Pharmacol Ther 2011;33(11):1202-8
63.Rastogi A, Wani S, Gupta N, Singh V, Gaddam S, Reddymasu S,
Ulusarac O, Fan F, Romanas M, Dennis KL, Sharma P, Bansal A,
Oropeza-Vail M, Olyaee M. A prospective, single-blind, randomized,
controlled trial of EUS-guided FNA with and without a stylet.
Gastorintest Endosc 2011, April 23
7
64.Wani S, Falk G, Hall M, Gaddam S, Wang A, Gupta N, Singh M,
Singh V, Chuang KY, Boolchand V, Gavini H, Kuczynski J, Sud P,
Reddymasu S, Bansal A, Rastogi A, Mathur SC, Young P, Cash
B, Lieberman DA, Sampliner RE, Sharma P. Patients with
nondysplastic Barrett’s esophagus have low risks for developing
dysplasia or esophageal adenocarcinoma. Clin Gastroenterol
Hepatol, 2011, 9(3):220-7
65.Sharma P, Johnson D. A., Monyak J.T., Illueca M. Race affects
healing of erosive oesophagitis in patients treated with proton
pump inhibitors. Alimentary Pharmacology and Therapeutics 2011,
34, 487-492
66.Shaheen NJ, Overholt BF, Sampliner RE, Wolfsen HC, Wang KK,
Fleischer DE, Sharma VK, Eisen GM, Fennerty MB, Hunter JG,
Bronner MP, Goldblum JR, Bennett AE, Mashimo H, Rothstein RI,
Gordon SR, Edmundowicz SA, Madanick RD, Peery AF, Muthusamy
VR, Chang KJ, Kimmey MB, Spechler SJ, Siddiqui AA, Souza RF,
Infantolino A, Dumot JA, Falk GW, Galanko JA, Jobe BA, Hawes
RH, Hoffman BJ, Sharma P, Chak A, Lightdale CJ. Durability of
Radiofrequency Ablation in Barrett’s Esophagus with
Dysplasia. Gastroenterology 2011 Aug: 141(2):460-8
67.Rastogi A, Early DS, Gupta N, Bansal A, Singh V, Ansstas M,
Jonnalagadda SS, Hovis CE, Gaddam S, Wani SB,
Edmundowicz SA, Sharma P. Randomized, controlled trial of
standard-definition white-light, and narrow-band imaging
colonoscopy for the detection of colon polyps and prediction of
polyp histology. Gastrointest Endosc 2011 Sep 74(3):593-602.
68.Gupta N, Bansal A, Wani SB, Gaddam S, Rastogi A, Sharma P.
Endoscopy for upper GI cancer screening in the general
population: a cost-utility analysis. Gastrointest Endosc 2011 Sep
74(3):610-624
69.Wallace M, Lauwers GY, Chen Y, Dekker E, Fockens P, Sharma P,
Meining A. Miami classification for probe-based confocal laser
endomicroscopy. Endosc 2011; 43:882-891
70.Wani S, Falk GW, Posr J, Yerian L, Hall M, Wang A, Gupta N,
Gaddam S, Singh M, Singh V, Chuang KY, Boolchand V, Gavini H,
Kuczynski J, Sud P, Bansal A, Rastogi A, Mathur SC, Young P,
Cash B, Goldblum J, Lieberman DA, Sampliner RE, Sharma P.
Risk factors for progression of low-grade dysplasia in patients with
Barrett’s esophagus Gastroenterol. 2011;141:1179-1186
71.Sharma P, Meining AR, Coron E, Lightdale CJ, Wolfsen HC,
Bansal A, Bajbouj M, Galmiche JP, Abrams A, Rastogi A, Gupta
N, Michalek JE, Lauwers GY, Wallace MB.
Real-time increased detection of neoplastic tissue in Barrett’s
esophagus with probe-based confocal laser endomicroscopy: final
results of an international multicenter, prospective, randomized,
controlled trial. Gastrointest Endosc. 2011; 74:465-472
72.Singh M, Bansal A, Curvers WL, Kara MA, Wani SB, Alvarez Herrero
L, Lynch CR, van Kouwen MCA, Peters FT, Keighley JD, Rastogi A,
Pondugula K, Kim R, Singh V, Gaddam A, Bergman JJ, Sharma P.
Observer agreement in the assessment of narrowband imaging
8
system surface patterns in Barrett’s esophagus: a multicenter
study. Endosc.2011;43:745-751
73.Gaddam S, Mathur SC, Singh M, Arora J, Wani SB, Gupta N,
Overhiser A, Rastogi A, Singh V, Desai N, Hall SB, Bansal A,
Sharma P. Novel Probe-Based Confocal Laser
Endomicroscopy Criteria and Interobserver Agreement for the
Detection of Dysplasia in Barrett’s Esophagus. Am J
Gastroenterol 2011;106:1961-1969
74.Gupta N, Bansal A, Rao D, Early DS, Jonnalagadda S,
Edmundowicz SA, Sharma P, Rastogi A. Accuracy of in vivo
optical diagnosis of colon polyp histologyby narrow-band
imaging in predicting colonoscopy surveillance intervals.
Gastrointest Endosc. 2012;75(3):494-502
75.Rastogi A, Bansal A, Rao DS, Gupta N, Wani SB, Shipe T,
Gaddam S, Singh V, Sharma P. Higher adenoma detection rates
with cap-assisted colonoscopy: a randomised controlled trial Gut
Description:PRATEEK SHARMA, MD, FACP, FACG. Division of Gastroenterology and Hepatology. University of Kansas School of Medicine. VA Medical Center.
