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About Nuclear Trafficking in Health and Disease: Sciencedirect
1) The document discusses nuclear trafficking of molecules between the nucleus and cytoplasm through nuclear pore complexes. 2) It describes how large molecules require nuclear transport receptors and the RanGTP/GDP gradient to facilitate import into and export out of the nucleus. 3) The document suggests that regulated nucleocytoplasmic trafficking plays an important role in cellular signaling pathways and that disruptions can lead to disease, including tumorigenesis through mislocalization of oncogenes and tumor suppressors.
Detailed Information
| Author: | ['Maria'] |
|---|---|
| Publication Year: | 2019 |
| Pages: | 8 |
| Language: | English |
| Format: | |
| Price: | FREE |
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