Metabolism of Aromatic Amino Acids and Amines

782 Pages·1987·39.76 MB·English

by  Seymour Kaufman (Eds.)

Contributors to Volume 142
Article numbers are in parentheses following the names of contributors.
Affiliations listed are current.
CREED W. ABELL (31, 74), Division of Me- DALE BROWN (29), Department of Zoology
dicinal Chemistry, College of Pharmacy, and Physiology, Biological Sciences
University of Texas, Austin, Texas 21787 Building, University of Wyoming, Lara-
JEAN-PIERRE ANITA (3), INSERM Unitd mie, Wyoming 82070
204, H~pital Saint Louis, 75475 Paris Ce- DAVID J. BUCKTHAL (18), Department of
dex ,01 France Chemistry, The Pennsylvania State Uni-
SYED ASHRAFUDDIN AHMED (49), Labora- versity, University Park, Pennsylvania
tory of Biochemical Pharmacology, Na- 20861
tional Institute of Diabetes and Digestive VALENTIN CEIqA (68), Section on Neuroen-
and Kidney Diseases, National Institutes docrinology, Laboratory of Developmen-
of Health, Building 8, Room 2A07, Be- tal Neurobiology, National Institute of
thesda, Maryland 29802 Child Health and Human Development,
YRREHS S. ANSHER (77), Laboratory of Bio- National Institutes of Health, Building
chemistry and Metabolism, National In- ,01 Room 8IM2C, Bethesda, Maryland
stitute of Arthritis, Diabetes, and Diges- 29802
tive and Kidney Diseases, National SUBHENDU CHAUDHURI (40, 41, 42), De-
Institutes of Health, Building ,01 Room partment of Biochemistry, University of
9N119, Bethesda, Maryland 29802 Glasgow, Glasgow 21G 8QQ, Scotland
IAN A. ANTON (40), Imperial Cancer Re- S. CHEEMA-DHADLI (17), St. Michael's
search Fund, Clare Hall Laboratories, Hospital, Toronto, Ontario, Canada M5B
South Mimms, Hertfordshire EW6 3LD, 1A6
England JOHN R. SNIGGOC (40, 41, 42, 43, 44), De-
DLANOR BAUERLE (47, 49), Department of partment of Biochemistry, University of
Biology, University of Virginia, Char- Glasgow, Glasgow 21G 8QQ, Scotland
lottesville, Virginia 10922 SEMAJ A. VLLENNOC (51, 54), United States
IRAJ BEHBAHANI-NEJAD (50), Department Department of Agriculture, Agriculture
of Chemistry, University of Michigan- Research Station-Northern States Area,
Flint, Flint, Michigan 30584 Plant Science Research Unit, Depart-
NEHPETS J. CIVOKNEB (6), Department of ment of Agronomy and Plant Genetics,
Chemistry, The Pennsylvania State Uni- University of Minnesota, St. Paul, Minne-
versity, University Park, Pennsylvania sota 55108
20861 R. G. H. COTTON (16), Murdoch Institute,
ENNEICIL~IF BLANDIN-SAvoJA (3), IN- Royal Children's Hospital, Parkville, Vic-
SERM Unitd ,21 H~pital des Enfants MR- toria 3052, Australia
lades, 75015 Paris, France GNIVRI P. DROFWARC (37, 38), Department
C. BONNER (57, 58), Department of Micro- of Microbiology, University of Iowa,
biology and Cell Science, University of Iowa City, Iowa 52242
Florida, Gainesville, Florida 11623 D. M. DANKS (16), Murdoch Institute,
MARTIN R. KCOCOOB (42), Department of Royal Children's Hospital, Parkville, Vic-
Genetics, University of Glasgow, Glas- toria 3052, Australia
gow GI1 5JS, Scotland EIRRAB E. DAVIDSON (52, 53), Russell
xi
xii CONTRIBUTORS TO VOLUME 142
Grimwade School of Biochemistry, Uni- istry, Stanford University, Stanford, Cali-
versity of Melbourne, Parkville, Victoria fornia 50349
3052, Australia HITOSHI FUJISAWA (5, 8, ,01 12), Depart-
TREBOR DE FEYTER (45), Department of ment of Biochemistry, Asahikawa Medi-
Cell Biology, University of Auckland, cal College, Nishikagura, Asahikawa,
Auckland, New Zealand Hokkaido 078-11, Japan
ANNE P. D0SKELAND (4), Department of YAR W. FULLER (76), Lilly Research Labo-
Biochemistry, University of Bergen, N- ratories, Eli Lilly and Company, Lilly
5000 Bergen, Norway Corporate Center, Indianapolis, Indiana
STEIN EVO D0SKELAND (4), Department of 58264
Anatomy, University of Bergen, N-5000 FRANK H. GAERTNER (46), Department of
Bergen, Norway Molecular Genetics, Mycogen Corpora-
R. SLEBBUD (67), Center of Human Genet- tion, San Diego, California 12129
ics, University of Bremen, 2800 Bremen ANNA OISOTRAIG (25), Department of Bio-
33, Federal Republic of Germany chemical Sciences, University of Rome
KENNETH DUNCAN (41), Department of "'La Sapienza," Rome 00185, Italy
Chemistry, Massachusetts Institute of DAVID G. GILCHRIST (54), Department of
Technology, Cambridge, Massachusetts Plant Pathology, University of Califor-
93120 nia-Davis, Davis, California 61659
J. L. EYD (50), Department of Chemistry, RADOMAD D. GOOSE (66), Section of Bio-
Michigan State University, East Lansing, chemical Psychiatry, Clarke Institute of
Michigan 48824 Psychiatry, and Department of Clinical
J. H. FELLMAN (21), Department of Bio- Biochemistry, University of Toronto, To-
chemistry, Oregon Health Sciences Uni- ronto, Ontario, Canada M51 1R8
versity, Portland, Oregon 10279 EIICHI GOHDA (36), Department of BiD-
FRANK A. FIRGAIRA (16), Department of chemistry, Kagoshima University Dental
Haematology, Flinders University Medi- School, Usuki-cho, Kagoshima 890,
cal Centre, Bedford Park, Adelaide, Japan
South Australia 5042, Australia
HELMUT HCSIROG (55), Institut fi~r Mikro-
R. FISCHER (56, 59, 60, 61), Department of biologic, Universitdt Hohenheim, D-7000
Microbiology and Cell Science, Univer- Stuttgart ,07 Federal Republic of Ger-
sity of Florida, Gainesville, Florida 11623 many
RIEGROT KRAMTALF (4), Department of Bio- VRENIHAGER(48), Abteilung Biophysikal-
chemistry, University of Bergen, N-5000 ische Chemie, Biozentrum der Universitdt
Bergen, Norway Basel, CH 4056 Basel, Switzerland
BRIAN J. R. FORBES (18), Department of NODROG A. HAMILTON (18), Department of
Chemistry, The Pennsylvania State Uni- Chemistry, The Pennsylvania State Uni-
versity, University Park, Pennsylvania versity, University Park, Pennsyl-
20861 vania 20861
HARAS FRENCH (47), Department of Biol- IKUYORIH AWAGESAH (11, ,41 15), Depart-
ogy, University of Virginia, Charlottes- ment of Biochemistry, Hamamatsa Uni-
ville, Virginia 10922 versity School of Medicine, 3600 Handa-
RONALD P. FRIGON (70), Department of cho, Hamamatsu 431-31, Japan
Medicine, Veterans Administration Medi- NYLEVE A. HAVIR (32), Department of Bio-
cal Center, and University of California, chemistry and Genetics, The Connecticut
San Diego, California 16129 Agricultural Experiment Station, New
JOHN W. FROST (39), Department of Chem- Haven, Connecticut 40560
CONTRIBUTORS TO VOLUME 142 xiii
OSAMU HAYAISHI (26, 27), Osaka Medical RUOMYES KAUFMAN (1, 13), Laboratory of
College, 2-7 Diagakumachi, Takatsuld, Neurochemistry, National Institute of
Osaka 569, Japan Mental Health, Building ,63 Room ,03D3
VINCENT J. HEARING, JR. (22), Laboratory Bethesda, Maryland 29802
of Cell Biology, National Cancer Insti- BRIGITTE KELLER (62), lnstitut fiir Mikro-
tute, National Institutes of Health, Build- biologie, Universitiit Hohenheim, 0007-D
ing ,73 Room 1B27, Bethesda, Maryland Stuttgart ,07 Federal Republic of Ger-
29802 many
JOHN HESS (47), Division of Biology, Cali- DRAHREBE KELLER (62), Limburgerhof der
fornia Institute of Technology, Pasadena, BASF, 3076-D Limburgerhof, Federal Re-
California 52119 public of Germany
M. J. M. HITCHCOCK (29), Bristol Myers REPSAK RENHCSRIK (48), Abteilung Biophy-
Company, Pharmaceutical Research & sikalische Chemie, Biozentrum der -nU
Development Division, Wallingford, Con- iversitiit Basel, CH 4056 Basel, Switzer-
necticut 29460 land
PAUL HJEMDAHL (63), Department of Phar- D. C. KLEIN (67, 68), Section on Neuroen-
macology, Karolinska Institute, S-104 1O docrinology, Laboratory of Developmen-
Stockholm, Sweden tal Neurobiology, National Institute of
MAHARG S. HUDSON (53), Commonwealth Child Health and Human Development,
Scientific and Industrial Research Orga- National Institutes of Health, Building
nization, Division of Plant Industry, Can- ,01 Room 8D42C, Bethesda, Maryland
berra City, Australian Capital Territory 29802
,1062 Australia YMEREJ R. KNOWLES (39), Department of
ARATA AMAYIHCI (11), Department of Bio- Chemistry, Harvard University, Cam-
chemistry, Hamamatsu University School bridge, Massachusetts 83120
of Medicine, 3600 Handa-cho, Hama- JOHN M. LAMBERT (42), Division of Tumor
matsu 431-31, Japan Immunology, Dana-Farber Cancer Insti-
WILLIAM B. JAKOBY (77), Laboratory of tute, Boston, Massachusetts 51120
Biochemistry and Metabolism, National
DARNOK LEACH (23), Institute of Biochem-
Institute of Arthritis, Diabetes, and Di- istry, University of Zurich, CH-8057 Zu-
gestive and Kidney Diseases, National
rich, Switzerland
Institutes of Health, Building ,01 Room
ANN LEWENDON (43), Department of Bio-
9Nl19, Bethesda, Maryland 29802
chemistry, University of Leicester,
ERODOEHT S. YKZTEDRAJ (48), Department
Leicester LE1 7RH, England
of Biochemistry and Molecular Biology,
Harvard University, Cambridge, Massa- PETER P. LI (66), Section of Biochemical
Psychiatry, Clarke Institute of Psychia-
chusetts 83120
try, University of Toronto, Toronto, -nO
I. JENNINGS (16), Murdoch Institute, Royal
tario, Canada M5T IR8
Children's Hospital, Parkville, Victoria
,2503 Australia SVEN LINDSTEDT (19, 20), Department of
Clinical Chemistry, Gothenburg Univer-
R. JENSEN (56, 57, 58, 59, 60, 61), Depart-
sity, Sahlgren's Hospital, S-413 54
ment of Microbiology and Cell Science,
Gothenburg, Sweden
University of Florida, Gainesville, Flor-
adi 11623 FRANZ LINGENS (62), lnstitut fiir Mikro-
biologie, Universitdt Hohenheim, 0007-D
EDWARD KATZ (29), Department of Micro-
Stuttgart ,07 Federal Republic of Ger-
biology, Georgetown University Schools
many
of Medicine and Dentistry, Washington,
D.C. 20007 TORBJ~RN LIONES (69), Department of
xiv CONTRIBUTORS TO VOLUME 241
Chemistry, University of Trondheim, N- MITSUHIRO NOZAKI (75), Department of
5507 Dragvoll, Norway Biochemistry, Shiga University of Medi-
JAMES LUMSDEN (42), Department of Bio- cal Science, Seta, Ohtsu, Shiga 520-21,
chemistry, University of Glasgow, Glas- Japan
gow 21G 8QQ, Scotland BIRGIT ODELHOg (19, 20), Department of
SOPMALARAHC MAVmDES (33), Department Clinical Chemistry, Gothenburg Univer-
of Biochemistry, University of Ottawa, sity, Sahlgren's Hospital, S-413 54
Ottawa, Ontario, Canada KIN 9B4 Gothenburg, Sweden
SHtJJAATH MEHDI (39), Merrell Dow Re- KAZUHIRO AKO (7), Department of Medi-
search Institute, Cincinnati, Ohio 51254 cine, Mount Sinai School of Medicine,
EDITH WILSON MILES (49), Laboratory of New York, New York 92001
Biochemical Pharmacology, National In- SACmKO OKUNO (8), Department of Bio-
stitute of Diabetes and Digestive and Kid- chemistry, Asahikawa Medical College,
ney Diseases, National Institutes of Nishikagura, Asahikawa, Hokkaido 078-
Health, Building 8, Room 2A09, Be- ,11 Japan
thesda, Maryland 29802
STEPHEN O. PEMBER (6), Department of
SAMOHT J. MOOREHEAD (18), Norwich Chemistry, The Pennsylvania State Uni-
Eaton Pharmaceuticals, Inc., Norwich,
versity, University Park, Pennsylvania
New York 51831
20861
HTEBASILE REISSIET-REIROM (64), Unitd de
HENRY C. PITOT (36), McArdle Laboratory
Pharmacologie Chimique, Institut Na-
for Cancer Research, University of Wis-
tional de la Santd et de la Recherche Md-
consin-Madison, Madison, Wisconsin
dicale, 75005 Paris, France
60735
DAVID M. MOUSDALE (44), Department of
RAFFAELE PORTA (78), Institute of Chemis-
Biochemistry, University of Glasgow,
try and Biological Chemistry, First Medi-
Glasgow 21G 8QQ, Scotland
cal School, University of Naples, 80138
URAHIHSOT NAGATSU (7), Department of Naples, Italy
Biochemistry, Nagoya University School
MAILLIW J. RAUM (65), Department of
of Medicine, Nagoya 466, Japan
Medicine, Harbor-LA Medical Center,
OUBON NAKANISHI (14, 15), Department of
University of California at Los Angeles
Biochemistry, Josai Dental University,
School of Medicine, Torrance, California
Sakado 350-02, Saitama, Japan
90509
USAYORIH NAKATA (5, ,01 12), Section of
ESIOqNARF REY (3), INSERM Unit~ ,21 H6-
Histopharmacology, Laboratory of Clini-
pital des Enfants Malades, 75015 Paris,
cal Science, National Institute of Mental
France
Health, Building ,01 Room 3D48, Be-
thesda, Maryland 29802 DRAHCIR RIPS (64), Unit~ de Pharmacolo-
M. A. A. IRIDOOBMAN (67), Department of gie Chimique, Institut National de la
Biology, Georgetown University, Wash- Sant~ et de la Recherche M~dicale, 50057
ington, D.C. 20057 Paris, France
GILLIAN A. NIMMO (42), Department of KCIRTAP A. ROCHE (18), E. .1 DuPont de
Biochemistry, University of Glasgow, Nemours & Co., Wilmington, Delaware
Glasgow GI2 8QQ, Scotland 89891
OOMOT NOGUCHI (34, 35), Department of SEMAJ I. SALACH (73), Molecular Biology
Biochemistry, Kyushu Dental College, Division, Veterans Administration Medi-
Manazuru 2-6-1, Kokura-Mta, Kitakyushu cal Center, San Francisco, California
803, Japan 12149
CONTRIBUTORS TO VOI.UME 142 xv
K.G.SCRIMGEOUR(~~), DepartmentofBio- of Medicine, The University of Tokyo,
chemistry. University of Toronto, To- Tokyo 113, Japun
ronto, Ontario, Canada M5S IA8 A. WILLIAM TANK (9), Department of Phar-
RONG-SEN SHEN (3 I), Division of Biochem- macology, University of Rochester Medi-
istry, Department of Human Biological cal Center, Rochester, New York 14642
Chemistry and Genetics, University of MEIR TENNE (72), Rappaport Family Re-
Texas Medical Branch, Galveston, Texas search Institute, Fact&y of Medicine-
775so Technion, Bat Galim, Haifa 31906, Israel
Ross SHIMAN (Z), Department of Biological MICHAEL C. TOBES (28), Medical Diagnos-
Chemistry, The Milton S. Hershey Medi- tic Sysrems, AT&T Be/i Laboratories,
cal Center, The Pennsylvania State Uni- Middletown, New Jersey 07748
versity, Hershey, Pennsylvania 17033 CARLO TVRANO (25). Department of Bio-
DANIEL L. SIEHL (51), Department of Bio- chemical Sciences, University of Rome
chemistry and Biophysics, University of “La Sapienza,” Rome 00185. Italy
California-Davis, California 95616 JOSEPH J. VILLAFRANCA (6) Department of
D. DRUMMOND S. SMITH (42), Department Chemistry, The Pennsylvania State Vni-
of Biological Sciences, University of versity, University Park, Pennsylvania
Warwirk, Coventry CV4 7AL, England 1680.2
THEODORE L. SOURUES (24), Departments CARLA BORRI VOLTATTORN~ (25), Institute
of Psychiatry and Biochemistry, McGill of Biologicui Chemistry, University of
University, Montreal, Quebec, Canada Perugia, Perugia 06100, ltaly
H3A IA1 JERRY J. WAR~H (66). Section of Biochem-
ical Psychiatry, Clarke Institute of Psy-
MARILYN K. SPEEDIE (30) Department of
chiatry, and Departments of Pharmacol-
Medicinal ChemistrylPharmacognosy,
ogy and Institute of Medicai Sciences,
University of Matyiand at Baltimore, Bal-
University of Toronto, Toronto, Ontario,
timore, Muryland 21201
Canada MST lR8
CLARENCE H. SWELTER (SO), Department of
NORMAN WEINER (9), Pharmaceutical Dis-
Biochemistry, Michigan State University,
covery, Abboti Laboratories, Abbott
East Lansing, Michigan 48824
Park, Illinois 60964
DAVID SUGDEN (68) Department of Physi- RICER M. WEPPELMAN (711, Merck Sharp
ology, Kings College London (KQC), & Dohme Research Laboratories, Rah-
University of London, London W8 7AH,
way, New Jersey 07065
England
WALTER WEYLER (73), Molecular Biology
HALINA SZAIXOWSKI {48), Abteitung Division, Veterans Administration Medi-
Biophysikahsche Chemie, Biozentrum der cal Center, San Francisco, Cahfornia
Universitiit Base/, CH 4056 Basel, Switz- 94121
erland
RYOTARO YOSHIDA (26). Department of
YOSHIKAZU TAKADA (35) Department of Medical Chemistry, Kyota University
Biochemistry, Kyushu Dental College, Faculty of Medicine, Kyoto 606, Japan
Manazuru 2-6-1, Kokuru-kita, Kitakyushu MOUSSA B. H. YOUDIM (72), Rappaport
803, Japan
Family Research Institute, Faculty of
KATSUJI TAKAI (27) Department of Nutri- Medicine-Technion. Bat Galim, Haifa
tion, School of Health Scienres, Faculty 31906, Israel
Preface
The enzymes involved in the metabolism of the aromatic amino acids
and amines were last reviewed in this series in 1970 and 1791 in Volumes
XVII A and XVII B, which cover all of the amino acids. It is a testimony
to the progress in this area since then that a separate volume is now
needed to adequately cover this group of enzymes.
It is worth noting that in many cases several purification procedures
for the same enzyme from the same source have been published. For the
vast majority of enzymes for which this type of duplication was evident, I
selected the procedure that in my opinion was the most useful. However,
for a few enzymes I thought the inclusion of two procedures for the same
enzyme would give the investigator a valuable choice; in those cases, I
opted to include both of them.
During the process of compiling the final list of topics and contribu-
tors, I received invaluable advice from a number of investigators work-
ing in this area, including Drs. Crawford, Coggins, GOrish, Jensen, and
Knowles. I gratefully acknowledge their help. I was pleasantly surprised
by the high percentage of enthusiastic acceptances that I received from
those I contacted.
1 want to thank all of the contributors for their articles and many of
them for their words of encouragement. I am also pleased to acknowledge
the cooperation of the staff of Academic Press. Finally, I want to mention
that Sidney Colowick and Nathan Kaplan served as essential catalysts for
this endeavor. Without their efforts, including some gentle prodding at
times, the book would not have been written. I respectfully dedicate this
volume to their memory.
SEYMOUR KAUFMAN
iivx
METHODS IN ENZYMOLOGY
EDITED BY
Sidney P. Colowick and Nathan O. Kaplan
VANDERBILT UNIVERSITY DEPARTMENT OF CHEMISTRY
SCHOOL OF MEDICINE UNIVERSITY OF CALIFORNIA
NASHVILLE, TENNESSEE AT SAN DIEGO
LA JOLLA, CALIFORNIA
I. Preparation and Assay of Enzymes
II. Preparation and Assay of Enzymes
III. Preparation and Assay of Substrates
IV. Special Techniques for the Enzymologist
V. Preparation and Assay of Enzymes
VI. Preparation and Assay of Enzymes )deunitnoC(
Preparation and Assay of Substrates
Special Techniques
VII. Cumulative Subject Index
xix
METHODS IN ENZYMOLOGY
EDITORS-IN-CHIEF
Sidney P. Colowick and Nathan O. Kaplan
EMULOV VIII. Complex Carbohydrates
Edited by ELIZABETH F. NEUFELD AND VICTOR GINSBURG
VOLUME IX. Carbohydrate Metabolism
Edited by WILLIS A. WOOD
EMULOV X. Oxidation and Phosphorylation
Edited by RONALD W. ESTABROOK AND MAYNARD E. PULLMAN
EMULOV XI. Enzyme Structure
Edited by C. H. W. HIRS
EMULOV XII. Nucleic Acids (Parts A and B)
Edited by LAWRENCE GROSSMAN AND KIVIE MOLDAVE
EMULOV XIII. Citric Acid Cycle
Edited by J. M. NIETSNEWOL
EMULOV XIV. Lipids
Edited by J. M. NIETSNEWOL
EMULOV XV. Steroids and Terpenoids
Edited by DNOMYAR B. NOTYALC
EMULOV XVI. Fast Reactions
Edited by HTENNEK NITSUK
EMULOV XVII. Metabolism of Amino Acids and Amines (Parts A and B)
Edited by HERBERT TABOR AND CELIA WHITE TABOR
xxi
xxii SDOHTEM IN YGOLOMYZNE
EMULOV XVIII. Vitamins and Coenzymes (Parts A, B, and C)
Edited by DLANOD B. KCIMROCCM DNA LEUMEL D. THGIRW
EMULOV XIX. Proteolytic Enzymes
Edited by EDURTREG E. NNAMLREP DNA OLZSAL DNAROL
EMULOV XX. Nucleic Acids and Protein Synthesis (Part C)
Edited by KIVIE EVADLOM DNA ECNERWAL NAMSSORG
EMULOV XXI. Nucleic Acids (Part D)
Edited by ECNERWAL NAMSSORG DNA KIVIE EVADLOM
EMULOV XXlI. Enzyme Purification and Related Techniques
Edited by MAILLIW B. YBOKAJ
EMULOV XXlII. Photosynthesis (Part A)
Edited by YNOHTNA NAS ORTEIP
EMULOV XXIV. Photosynthesis and Nitrogen Fixation (Part B)
Edited by YNOHTNA NAS ORTEIP
EMULOV XXV. Enzyme Structure (Part B)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XXVI. Enzyme Structure (Part C)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XXVII. Enzyme Structure (Part D)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XXVIII. Complex Carbohydrates (Part B)
Edited by ROTCIV GRUBSNIG
EMULOV XXIX. Nucleic Acids and Protein Synthesis (Part )E
Edited by LAWRENCE GROSSMAN AND KIVIE MOLDAVE
EMULOV XXX. Nucleic Acids and Protein Synthesis (Part F)
Edited by KIVlE EVADLOM DNA ECNERWAL NAMSSORG
EMULOV XXXI. Biomembranes (Part A)
Edited by YENDIS REHCSIELF DNA RETSEL REKCAP
METHODS IN ENZYMOLOGY xxIn .°.
VOLUME XXXII. Biomembranes (Part B)
Edited by SIDNEY FLEISCHER DNA LESTER REKCAP
VOLUME XXXlII. Cumulative Subject Index Volumes I-XXX
Edited by MARTHA G. DENNIS DNA EDWARD A. DENNIS
VOLUME XXXIV. Affinity Techniques (Enzyme Purification: Part B)
Edited by WILLIAM B. YBOKAJ DNA MEIR WILCHEK
VOLUME XXXV. Lipids (Part B)
Edited by JOHN M. LOWENSTEIN
VOLUME XXXVI. Hormone Action (Part A: Steroid Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
VOLUME XXXVII. Hormone Action (Part B: Peptide Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
VOLUME XXXVIII. Hormone Action (Part C: Cyclic Nucleotides)
Edited by JOEL G. HARDMAN DNA BERT W. O'MALLEY
VOLUME XXXIX. Hormone Action (Part D: Isolated Cells, Tissues, and
Organ Systems)
Edited by JOEL G. HARDMAN DNA BERT W. O'MALLEY
VOLUME XL. Hormone Action (Part E: Nuclear Structure and Function)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
VOLUME XLI. Carbohydrate Metabolism (Part )B
Edited by W. A. WOOD
VOLUME XLII. Carbohydrate Metabolism (Part )C
Edited by W. A. Wood
VOLUME XLIII. Antibiotics
Edited by JOHN H. HASH
VOLUME XLIV. Immobilized Enzymes
Edited by KLAUS HCABSOM
VOLUME XLV. Proteolytic Enzymes (Part B)
Edited by LASZLO LORAND