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Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development) PDF

275 Pages·2001·2.246 MB·English
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by Neil J. Clendeninn, Krzysztof Appelt| 2001| 275 pages| 2.246| English

About Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)

Cutting-edge investigators review the current status of the entire field, from the biology of MMPs through the current clinical studies. The authors include many leading scientists from pharmaceutical companies who present all the latest concepts and results on the preferred design strategies for MMP inhibitors, their molecular mechanisms, and their substrates. In addition, they fully describe their personal research on specific MMP inhibitors, detailing vanguard design strategies, their in vitro activity, the outcome of animal model studies and, where available, their toxicology, safety, efficacy in human clinical trials. Comprehensive and state-of-the-art, Matrix Metalloproteinase Inhibitors in Cancer Therapy offers basic and clinical investigators alike a richly informative summary of all the latest research on these powerful new drugs, and their high promise as emerging cancer therapeutics.

Detailed Information

Author:Neil J. Clendeninn, Krzysztof Appelt
Publication Year:2001
ISBN:9781592590117
Pages:275
Language:English
File Size:2.246
Format:PDF
Price:FREE
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