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Library Design, Search Methods, and Applications of Fragment-Based Drug Design PDF

197 Pages·2011·8.842 MB·English
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by Rachelle J. Bienstock (Eds.)| 2011| 197 pages| 8.842| English

About Library Design, Search Methods, and Applications of Fragment-Based Drug Design

Content: Overview : fragment based drug design -- Designing and searching fragment libraries -- Validation of reaction vectors for de novo design -- Design and application of fragment libraries for protein crystallography -- Ligand-based virtual screening using Bayesian inference network -- A computational fragment approach by mining the protein data bank: library design and bioisosterism -- Computational screening : docking -- A fragment based docking engine : eHiTS -- Fragment-based high-throughput docking and library tailoring -- Leads from fragments : fragment growing and linking -- Fragment-based high-throughput docking and library tailoring -- Fragment-based drug discovery for diseases of the central nervous system.

Detailed Information

Author:Rachelle J. Bienstock (Eds.)
Publication Year:2011
ISBN:9780841224933
Pages:197
Language:English
File Size:8.842
Format:PDF
Price:FREE
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