Table Of ContentVolume 51 ¢ Number 1 ¢ January 1993
PROSPECTS SYMPOSIUM
Introduction: Protein Phosphorylation and Signal Transduction in Bacteria
I Naka anced Stender tn hac pase as NRE aalasc ocoons NINA A RE GATE lata Maelo
A. CLASSICAL ATP-DEPENDENT KINASES
ATP-Dependent Protein Kinases in Bacteria
Alain J. Cozzone
The Isocitrate Dehydrogenase Phosphorylation Cycle: Regulation and Enzymology
David C. LaPorte
The Role of Phosphorylation of HPr, a Phosphocarrier Protein of the Phosphotransferase
System, in the Regulation of Carbon Metabolism in Gram-Positive Bacteria
Jonathan Reizer, Antonio H. Romano, and Josef Deutscher
Catabolite Repression in the Gram-Positive Bacteria: Generation of Negative Regulators of
Transcription
George C. Stewart
Eukaryotic-Like Protein Serine/ Threonine Kinases in Myxococcus xanthus, a
Developmental Bacterium Exhibiting Social Behavior
Jose Munoz-Dorado, Sumiko Inouye, and Masayori Inouye
B. SENSOR KINASE-RESPONSE REGULATORS
The Regulation of Nitrogen Utilization in Enteric Bacteria
Boris Magasanik
Response Regulation in Bacterial Chemotaxis
Gudrun S. Lukat and Jeffry B. Stock
Gene Regulation by Phosphate in Enteric Bacteria
B.L. Wanner
The Phosphorelay Signal Transduction Pathway in the Initiation of Bacillus subtilis
Sporulation
James A. Hoch
C. THE BACTERIAL PHOSPHOTRANSFERASE SYSTEMS
Regulatory Interactions Involving the Proteins of the Phosphotransferase System in Enteric
Bacteria
Milton H. Saier, Jr
Signal Transduction in Chemotaxis Mediated by the Bacterial Phosphotransferase System
Friedrich Titgemeyer
Three-Dimensional Structures of the Central Regulatory Proteins of the Bacterial
Phosphotransferase System, HPr and Enzyme IIA9!¢
Y. Chen, W.J. Fairbrother, and P.E. Wright
Transcriptional Regulation of the bg/ Operon of Escherichia coli Involves
Phosphotransferase System-Mediated Phosphorylation of a Transcriptional Antiterminator
Orna Amster-Choder and Andrew Wright :
ARTICLES
Okadaic Acid as an Inducer of the 78-kDa Glucose-Regulated Protein in 9L Rat Brain Tumor
Cells
Ming-Chin Hou, Chi-Hsiu Shen, Wen-Chuan Lee, and Yiu-Kay Lai
Volume 51 ¢ Number 1 ¢ January 1993
PROSPECTS SYMPOSIUM
Introduction: Protein Phosphorylation and Signal Transduction in Bacteria
I Naka anced Stender tn hac pase as NRE aalasc ocoons NINA A RE GATE lata Maelo
A. CLASSICAL ATP-DEPENDENT KINASES
ATP-Dependent Protein Kinases in Bacteria
Alain J. Cozzone
The Isocitrate Dehydrogenase Phosphorylation Cycle: Regulation and Enzymology
David C. LaPorte
The Role of Phosphorylation of HPr, a Phosphocarrier Protein of the Phosphotransferase
System, in the Regulation of Carbon Metabolism in Gram-Positive Bacteria
Jonathan Reizer, Antonio H. Romano, and Josef Deutscher
Catabolite Repression in the Gram-Positive Bacteria: Generation of Negative Regulators of
Transcription
George C. Stewart
Eukaryotic-Like Protein Serine/ Threonine Kinases in Myxococcus xanthus, a
Developmental Bacterium Exhibiting Social Behavior
Jose Munoz-Dorado, Sumiko Inouye, and Masayori Inouye
B. SENSOR KINASE-RESPONSE REGULATORS
The Regulation of Nitrogen Utilization in Enteric Bacteria
Boris Magasanik
Response Regulation in Bacterial Chemotaxis
Gudrun S. Lukat and Jeffry B. Stock
Gene Regulation by Phosphate in Enteric Bacteria
B.L. Wanner
The Phosphorelay Signal Transduction Pathway in the Initiation of Bacillus subtilis
Sporulation
James A. Hoch
C. THE BACTERIAL PHOSPHOTRANSFERASE SYSTEMS
Regulatory Interactions Involving the Proteins of the Phosphotransferase System in Enteric
Bacteria
Milton H. Saier, Jr
Signal Transduction in Chemotaxis Mediated by the Bacterial Phosphotransferase System
Friedrich Titgemeyer
Three-Dimensional Structures of the Central Regulatory Proteins of the Bacterial
Phosphotransferase System, HPr and Enzyme IIA9!¢
Y. Chen, W.J. Fairbrother, and P.E. Wright
Transcriptional Regulation of the bg/ Operon of Escherichia coli Involves
Phosphotransferase System-Mediated Phosphorylation of a Transcriptional Antiterminator
Orna Amster-Choder and Andrew Wright :
ARTICLES
Okadaic Acid as an Inducer of the 78-kDa Glucose-Regulated Protein in 9L Rat Brain Tumor
Cells
Ming-Chin Hou, Chi-Hsiu Shen, Wen-Chuan Lee, and Yiu-Kay Lai
Low Fluences of Ultraviolet Irradiation Stimulate HeLa Cell Surface Aminopeptidase and
Candidate “TGFaase” Activity
S.B. Brown, D. Krause, and K.A.O. Ellem
Acidic Fibroblast Growth Factor Gene 5’ Non-Coding Exon and Flanking Region From
Hamster DDT1 Cells: Identification of the Promoter Region and Transcriptional Regulation
by Testosterone and aFGF Protein
Jeffrey A. Hall, Marie A. Harris, Richard Intres, and Stephen E. Harris
Volume 51 ¢ Number 2 « February 1993
IN MEMORIAM
Dedication: William Leo McGuire
Bert W. O’Malley
VIEWPOINT
Multiple Mechanisms for Regulation of Steroid Hormone Action
Kerry L. Burnstein and John A. Cidlowski
PROSPECTS
Estrogen Receptor Mutations in Breast Cancer
S.A.W. Fuqua, G.C. Chamness, and W.L. McGuire
On the Mechanism of DNA Binding by Nuclear Hormone Receptors: A Structural and
Functional Perspective
Leonard P. Freedman and Ben F. Luisi
Mechanisms of Transcriptional Activation by Steroid Hormone Receptors
Aria Baniahmad and Ming-Jer Tsai
ARTICLES
Characteristics of DNA Replication in Isolated Nuclei Initiated by an Aprotinin-Binding
Protein
Frederick D. Coffman, Kerin L. Fresa, Meera Hameed, and Stanley Cohen
4-Quinolones Cause a Selective Loss of Mitochondrial DNA From Mouse L1210 Leukemia
Cells
Jeffrey W. Lawrence, Sandra Darkin-Rattray, Fan Xie, Allen H. Neims, and Thomas C. Rowe
Expression of Histone and Alkaline Phosphatase Genes in UMR 106-01 Rat Osteoblast-Like
Cells Exposed to the Hoechst Dye H33342
M.H. Zheng, S. Wysocki, J.M. Papadimitriou, and D. Wood
Effect of Retinyl Acetate on the Assembly of the Fibronectin Extracellular Matrix and the
Processing of the Fibronectin Receptor 6 Subunit of Confluent C3H/10T1/2 Mouse Embryo
Fibroblasts
Satoshi S. Suzuki and Lawrence H. Piette
Selection of Malonate-Resistant Stromal Cell-Derived Osteoprogenitor Cells In Vitro
Benjamin Y. Klein, Irena Gal, and David Segal
Temporally Different Poly(Adenosine Diphosphate-Ribosylation) Signals Are Required for
DNA Replication and Cell Division in Early Embryos of Sea Urchins
Maria Imschenetzky, Martin Montecino, and Marcia Puchi
Identification of a Role of the Vitronectin Receptor and Protein Kinase C in the Induction of
Endothelial Cell Vascular Formation
Cynthia M. Davis, Susan C. Danehower, Antonio Laurenza, and J. Leslie Molony
Detection and Characterization of Low Abundance Cellular Proteins That Specifically
Increase Upon Loss of the Metastatic Phenotype
Sheila M. Nielsen-Preiss and James P. Quigley
Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies Affecting Signal
Transduction
Hans-Albert Reins, Gerhard Steinhilber, Brigitte Freiberg, and F. Alfred Anderer
Volume 51 « Number 3 ¢ March 1993
VIEWPOINT
Advances in Cellular Construction
Glenn F. Spaulding, J. Milburn Jessup, and Thomas J. Goodwin
PROSPECTS
Utilization of Microgravity Bioreactors for Differentiation of Mammalian Skeletal Tissue
Brenda J. Klement and Brian S. Spooner
Cultivation of Cell-Polymer Cartilage Implants in Bioreactors
L.E. Freed, G. Vunjak-Novakovic, and R. Langer
Use of Microgravity Bioreactors for Development of an In Vitro Rat Salivary Gland Cell
Culture Model
Marian L. Lewis, Debra M. Moriarity, and P. Samuel Campbell
Studies of Chondrogenesis in Rotating Systems
P. Jackie Duke, Elizabeth L. Daane, and Dina Montufar-Solis
Three-Dimensional Growth and Differentiation of Ovarian Tumor Cell Line in High Aspect
Rotating-Wall Vessel: Morphologic and Embryologic Considerations
Jeanne L. Becker, Tacey L. Prewett, Glenn F. Spaulding, and Thomas J. Goodwin
Prospects for Use of Microgravity-Based Bioreactors to Study Three-Dimensional
Host-Tumor Interactions in Human Neoplasia
J.M. Jessup, T.J. Goodwin, and G. Spaulding
Reduced Shear Stress: A Major Component in the Ability of Mammalian Tissues to Form
Three-Dimensional Assemblies in Simulated Microgravity
T.J. Goodwin, T.L. Prewett, David A. Wolf, and G.F. Spaulding
ARTICLES
pH Sensitivity of Epidermal Growth Factor Receptor Complexes
Marissa Nunez, Kevin H. Mayo, Cindy Starbuck, and Douglas Lauffenburger
A Point Mutation in the 5’ Splice Region of Intron 7 Causes a Deletion of Exon 7 in
Adenosine Deaminase mRNA
Hiroshi Kawamoto, Kazuhiko Ito, Saburo Kashii, Sumie Monden, Masahiro Fujita, Mihoko
Norioka, Yoshiki Sasai, and Minoru Okuma
Binding of Tissue-Type Plasminogen Activator to Human Melanoma Cells
Jozef Bizik, Ross W. Stephens, Marta Grofova, and Antti Vaheri
DNA Repair and Repair Fidelity in Metastatic Variants of the B16 Murine Melanoma
B.A. Usmani, J. Lunec, and G.V. Sherbet
Binding and Subcellular Distribution of Cyclosporine in Human Fibroblasts
David A. Tipton and Mustafa Kh. Dabbous
Drosophila Acidic Ribosomal Protein rpA2: Sequence and Characterization
Pamela F. Olson, Tuula Salo, Katherine Garrison, and John H. Fessler
High Mannose Type N-Linked Oligosaccharides on Endothelial Cells May Influence 62
Integrin Mediated Neutrophil Adherence In Vitro
P. Sriramarao, Elaine Berger, J. David Chambers, Karl-E. Arfors, and Kurt R. Gehisen
Enhanced Phosphorylation of a 65 kDa Protein Is Associated With Rapid Induction of
Stress Proteins in 9L Rat Brain Tumor Cells
Yiu-Kay Lai, Chi-Hsiu Shen, Ting-Jen Cheng, Ming-Ching Hou, and Wen-Chuan Lee
Volume 51 ¢ Number 4 « April 1993
PROSPECTS
Effects of Electromagnetic Field Exposure on Gene Transcription
Jerry L. Phillips
Beneficial Effects of Electromagnetic Fields
C. Andrew L. Bassett
Static and Extremely Low Frequency Electromagnetic Field Exposure: Reported Effects on
the Circadian Production of Melatonin
Russel J. Reiter
Prospects on Clinical Applications of Electrical Stimulation for Nerve Regeneration
Betty F. Sisken, Janet Walker, and Michael Orgel
Biological Effects of Electromagnetic Fields
W. Ross Adey
Environmental Magnetic Fields: Influences on Early Embryogenesis
lvan L. Cameron, W. Elaine Hardman, Wendell D. Winters, Selma Zimmerman,
and Arthur M. Zimmerman
Electroporation: A General Phenomenon for Manipulating Cells and Tissues
James C. Weaver
Electromagnetic Fields and Celis
Reba Goodman, Yuri Chizmadzhev, and Ann Shirley-Henderson
ARTICLES
The Possible Involvement of Protein Phosphatase 1 in Thrombin-Induced Ca?* Influx of
Human Platelets
Kouhei Murata, Masato Sakon, Jun-ichi Kambayashi, Masao Yukawa, Yoshiko Yano,
Kazumasa Fujitani, Tomio Kawasaki, Eiichi Shiba, and Takesada Mori
Derivatives of 4-Amino-3,6-Disulfonato-1 ,8-Naphthalimide Inhibit Reverse Transcriptase
and Suppress Human and Feline Immunodeficiency Virus Expression in Cultured Cells
Darryl Rideout, Raymond Schinazi, C. David Pauza, Kathleen Lovelace, Lin-Chang Chiang,
Theodora Calogeropoulou, Michael McCarthy, and John H. Elder
Fatty Acyl-CoA Binding Activity of the Nuclear Thyroid Hormone Receptor
Qiulin Li, Naoki Yamamoto, Seiji Morisawa, and Akira Inoue
Homotypic Leukocyte Aggregation Triggered by a Monoclonal Antibody Specific for a
Novel Epitope Expressed by the Integrin 81 Subunit: Conversion of Nonresponsive Cells by
Transfecting Human Integrin a4 Subunit CDNA
John L. Bednarczyk, James N. Wygant, Margit C. Szabo, Laura Molinari-Storey, Mark Renz,
Sherman Fong, and Bradley W. Mcintyre
Differential Expression of the Chromosomal High Mobility Group Proteins 14 and 17 During
the Onset of Differentiation in Mammalian Osteoblasts and Promyelocytic Leukemia Cells
Abdul Rauf Shakoori, Thomas A. Owen, Victoria Shalhoub, Janet L. Stein, Michael Bustin,
Gary S. Stein, and Jane B. Lian
Isolation and Characterization of Deteriosomes From Rat Liver
Kening Yao, Xiumei Wu, John E. Thompson, and John C. Carlson
Author Index to Volume 51
Subject Index to Volume 51
