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About Innate Response Activator B Cells Protect Against Sepsis 2012 - Science
This study identifies a population of innate response activator (IRA) B cells that produce granulocyte-macrophage colony-stimulating factor (GM-CSF) and protect against microbial sepsis. IRA B cells increase in number during inflammation and depend on pattern-recognition receptors. Specific deletion of IRA B cells impairs bacterial clearance, triggers a cytokine storm, and causes septic shock. These findings position IRA B cells as important gatekeepers of bacterial infection.
Detailed Information
| Author: | ['Jro Klf'] |
|---|---|
| Publication Year: | 2021 |
| Pages: | 6 |
| Language: | English |
| Format: | |
| Price: | FREE |
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