Table Of ContentHigh-Resolution
CT of the Lung
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High-Resolution
CT of the Lung
F I F T H E D I T I O N
W. Richard Webb, MD
Professor Emeritus of Radiology and Biomedical Imaging
Emeritus Member, Haile Debas Academy of Medical Educators
University of California San Francisco
San Francisco, California
Nestor L. Müller, MD, PhD
Professor Emeritus of Radiology
Department of Radiology, University of British Columbia
Vancouver, British Columbia, Canada
David P. Naidich, MD, FACR, FAACP
Professor of Radiology and Medicine
New York University
Langone Medical Center
New York, New York
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Library of Congress Cataloging-in-Publication Data
Webb, W. Richard (Wayne Richard), 1945- author.
High-resolution CT of the lung / W. Richard Webb, Nestor L. Müller, David P. Naidich. — Fifth edition.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-1-4511-7601-8 (alk. paper)
I. Müller, Nestor Luiz, 1948- , author. II. Naidich, David P., author. III. Title.
[DNLM: 1. Lung—radiography. 2. Tomography, X-Ray Computed. 3. Lung Diseases—pathology.
WF 600]
RC734.T64
616.2’407572—dc23
2014003388
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DEDICATION
To my father, who encouraged my curiosity and taught
me to figure things out
––WRW
To my wife, Isabela, and my children—Alison, Phillip,
and Noah Müller
––NLM
To Jocelyn, whose constant love and support has always
been my greatest inspiration
––DPN
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Contributing Authors
Brett M. Elicker, MD
Associate Professor of Clinical Radiology and Biomedical Imaging
Chief, Cardiac and Pulmonary Imaging
University of California San Francisco
San Francisco, California
Myrna C. B. Godoy, MD, PhD
Assistant Professor of Radiology
University of Texas
MD Anderson Cancer Center
Houston, Texas
C. Isabela S. Müller, MD, PhD
Department of Radiology
Delfin Clinic
Salvador, Bahia, Brazil
vii
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Preface
During the past 25 years, high-resolution CT (HRCT) has of an inch thick, and, to our knowledge, referenced every
become established as an indispensable tool in the evalu- known paper on HRCT. From our perspective, it was the
ation of patients with diffuse lung disease. HRCT is now most important thing we had ever done.
commonly used in clinical practice to detect and char- That is how things start. Maybe that is the best way
acterize a variety of lung abnormalities. In the approxi- things should start. It was certainly fun and rewarding
mately 5 years since our fourth edition was published, for each of us. And we three have stuck together over the
considerable progress has taken place in the understand- years, out of our combined respect, admiration, friend-
ing of diffuse lung diseases and the recognition of new ship, and good humor. Each one of us believes that we
entities and their nature, causes, and characteristics. learned more from our collaboration than we taught.
Without doubt, HRCT has played a fundamental role in In this edition, we have incorporated an update and
contributing to this progress and has become essential to review of numerous recent advances in the classifica-
the diagnosis of a number of diffuse diseases. tion and understanding of diffuse lung diseases and their
This fifth edition continues what the three of us, in- HRCT features. Recent technical modifications in obtain-
dependently, in conjunction, and with each other’s en- ing HRCT have also been reviewed, most notably the use
couragement and support, began some 30 years ago. The of helical HRCT and dose-reduction techniques. We hope
photograph of the three of us below was taken by a local the reader will find these changes and updates helpful.
resident at the 1989 Diagnostic Course in Davos, on a walk As is our wont, we have reorganized our discussions into
we took on the promenade above the Sweitzerhof on the new sections and chapters, which we feel best presents the
day of our arrival, when as junior faculty, we were more most important topics in HRCT diagnosis for reference
than a little anxious about teaching along with such im- and learning.
portant and impressive chest radiologists as Fraser, Felson, A new section has been added at the end of the book
Greenspan, Milne, Flowers, Heitzman, and many others. to provide a general review of HRCT, including an illus-
trated glossary of HRCT terms and a chapter providing
a compilation of the common and typical appearances of
the most common diffuse lung diseases encountered in
clinical practice. These sections are intended to provide
an illustrated index to the detailed descriptions of dis-
eases found elsewhere in the book.
It is with a great deal of pride that we complete our
fifth edition of this book, which has occupied so much of
our thoughts, efforts, and time over the years. This task
is accomplished in the hope that this book will encour-
age future generations of thoracic imagers to develop
mutually productive relationships with friends and col-
leagues, in order to explore important questions in our
At this meeting, we each spoke about the use of HRCT,
understanding of the role of imaging in the assessment of
which, at the time, was a little-known technique that
thoracic disease.
was regarded with skepticism by many radiologists. We
To this end, we acknowledge the contributions of three
learned from each other as we spoke, compared slides
esteemed colleagues, our former fellows, who have au-
in the speaker-ready room, and gained confidence from
thored parts of this book. Their efforts have greatly in-
our shared opinions. At this meeting, we began thinking
spired our own enthusiasm for the considerable task of
about a collaboration that would combine our experience
bringing this edition to fruition.
and thoughts about this new modality and its potential
uses. Our first edition of this book was published in late W. RichaRd Webb NestoR L. MüLLeR
1991, with a grand total of 159 pages. It was a quarter david P. Naidich
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Description:Looking for the seminal guide to HRCT and lung abnormalities? Get the newly revised and updated 5th edition of High-Resolution CT of the Lung, the leading reference on the use of high-res computed tomography for diagnosis and assessment of diffuse lung diseases. Written by leading experts in the fie