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Fluoropyrimidines in Cancer Therapy (Cancer Drug Discovery and Development) PDF

340 Pages·2002·2.236 MB·English
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by Youcef M. Rustum| 2002| 340 pages| 2.236| English

About Fluoropyrimidines in Cancer Therapy (Cancer Drug Discovery and Development)

Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.

Detailed Information

Author:Youcef M. Rustum
Publication Year:2002
ISBN:9781592593378
Pages:340
Language:English
File Size:2.236
Format:PDF
Price:FREE
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