Table Of ContentColor Atlas and Text of
HISTOLOGY
SEVENTH EDITION
Color Atlas and Text of
HISTOLOGY
SEVENTH EDITION
Leslie P. Gartner, PhD
Professor of Anatomy (Retired)
Department of Biomedical Sciences
Baltimore College of Dental Surgery
Dental School
University of Maryland
Baltimore, Maryland
Acquisitions Editor: Crystal Taylor
Development Editors: Andrea Vosburgh and Kelly Horvath
Editorial Coordinator: Annette Ferran
Editorial Assistant: Brooks Phelps
Marketing Manager: Mike McMahon
Production Project Manager: Bridgett Dougherty
Design Coordinator: Holly McLaughlin
Manufacturing Coordinator: Margie Orzech
Prepress Vendor: SPi Global
7th edition
Copyright © 2018 Wolters Kluwer
Copyright © 2014, 2009, 2006, 2000, 1994, 1990 Lippincott Williams & Wilkins, a Wolters Kluwer
business. All rights reserved. This book is protected by copyright. No part of this book may be reproduced
or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic
copies, or utilized by any information storage and retrieval system without written permission from the
copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing
in this book prepared by individuals as part of their official duties as U.S. government employees are not
covered by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two
Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at [email protected], or via
our website at lww.com (products and services).
9 8 7 6 5 4 3 2 1
Printed in China
Translations:
Chinese (Taiwan): Ho-Chi Book Publishing Company
Chinese (Mainland China): Liaoning Education Press/CITIC
Chinese (Simplified Chinese): CITIC/Chemical Industry Press
French: Wolters Kluwer France
Greek: Parissianos
Indonesian: Binarupa Publisher
Italian: Masson Italia; EdiSES
Japanese: Igaku-Shoin; Medical Sciences International (MEDSI)
Korean: E*Public, Co., Ltd
Portuguese: Editora Guanabara Koogan
Russian: Logosphera
Spanish: Editorial Medica Panamericana; Gestora de Derechos Autorales; Libermed Verlag
Turkish: Gunes Bookshops
Vietnamese: Hanoi Medical University
Library of Congress Cataloging-in-Publication Data
Names: Gartner, Leslie P., 1943- author.
Title: Color atlas and text of histology / Leslie P. Gartner.
Description: Seventh edition. | Philadelphia : Wolters Kluwer, [2018] | Includes index.
Identifiers: LCCN 2016058316 | ISBN 9781496346735
Subjects: | MESH: Histology | Atlases
Classification: LCC QM557 | NLM QS 517 | DDC 611/.0180222—dc23 LC record available at
https://lccn.loc.gov/2016058316
This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied,
including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals’
examination of each patient and consideration of, among other things, age, weight, gender, current or prior
medical conditions, medication history, laboratory data and other factors unique to the patient. The
publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare
professionals, and not the publisher, are solely responsible for the use of this work including all medical
judgments and for any resulting diagnosis and treatments.
Given continuous, rapid advances in medical science and health information, independent professional
verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and
treatment options should be made and healthcare professionals should consult a variety of sources. When
prescribing medication, healthcare professionals are advised to consult the product information sheet (the
manufacturer's package insert) accompanying each drug to verify, among other things, conditions of use,
warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if
the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the
maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any
injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise,
or from any reference to or use by any person of this work.
LWW.com
To my wife Roseann,
my daughter Jennifer,
and my mother Mary.
LPG
REVIEWERS
Rocky Behniwal
Student
Ross University School of Medicine
Dominica, West Indies
Amber Hale, PhD
Assistant Professor
Department of Biology
McNeese State University
Lake Charles, Louisiana
Wanda Lai
Student
Oakland University William Beaumont School of Medicine
Rochester, Michigan
Lisa M. J. Lee, PhD
Associate Professor
Department of Cell and Developmental Biology
University of Colorado School of Medicine
Aurora, Colorado
Jamie Qualls
Student
Michigan State University College of Osteopathic Medicine
East Lansing, Michigan
Zak Richey
Student
Rosalind University of Medicine and Science
Chicago, Illinois
Dilisha Rodrigopulle
Student
Touro College of Osteopathic Medicine
Middletown, New York
Guy Sovak, PEng, BSc, MSc, PhD
Assistant Professor
Division of Anatomy and Histology
Canadian Memorial Chiropractic College
Toronto, Ontario, Canada
PREFACE TO THE SEVENTH EDITION
I am very pleased to be able to present the seventh edition of Color Atlas and
Text of Histology, an atlas that has been in continuous use since its first
publication as a black and white atlas in 1987. The success of that atlas
prompted us to revise it considerably, retake all of the images in full color,
change its name, and publish it in 1990 under the title Color Atlas of Histology.
In the past 27 years, the atlas has undergone many changes. We added color
paintings, published a corresponding set of Kodachrome slides, and added more
material to the text. The advent of high-resolution digital photography allowed
us to reshoot all of the photomicrographs for the fourth edition.
Major changes are introduced in the seventh edition. The most exciting
change is that I have completely rewritten, reorganized, and enhanced the textual
material and added new tables to such an extent that it can be used not only as an
atlas but also as review book to study for course examinations as well as for the
USMLE Step 1. Because clinical content is essential to success both in
navigating the integrated medical curriculum and in future practice, this atlas
continues to feature numerous Clinical Consideration boxes that describe and
illustrate relevant pathology. I have also included a new feature in the form of a
new appendix, “Tissues that Resemble Each Other,” that compares and contrasts
40 light micrographs of tissues that may easily be mistaken for the other.
Probably the second most exciting change that was introduced into this edition is
the addition of 124 new light micrographs and 4 new electron micrographs that
assist the student in reviewing the histologic images in every chapter but the
first. Moreover, the new chapter on Histologic Techniques (Chapter 20) was
created from and expands on the sixth-edition appendix.
As in the previous editions, most of the photomicrographs of this atlas are of
tissues stained with hematoxylin and eosin. All indicated magnifications in light
and electron micrographs are original magnifications. Many of the sections were
prepared from plastic-embedded specimens, as noted. Most of the exquisite
electron micrographs included in this atlas were kindly provided by my
colleagues throughout the world as identified in the legends.
For examination preparation purposes, the online Student Resources for the
atlas include over 300 additional photomicrographs with more than 700
interactive questions organized in a fashion to facilitate the student's learning and
1
review for practical exams. Additionally, I have included approximately 100
USMLE Step 1 format multiple-choice questions, based on photomicrographs
created specifically for the questions.
The most dramatic change to the seventh edition, at least to me, is that my
coauthor, Dr. James L. Hiatt, decided not to be associated with the writing of this
edition of our Atlas. Jim retired from active teaching 20 years ago and decided to
make his retirement complete and devote himself to other endeavors. Over the
years, Jim and I wrote 24 research articles, 47 abstracts, and, counting new
editions, 22 textbooks together. It was a very pleasant and fruitful association,
and I sorely miss this long-term professional partnership. Needless to say, our
personal friendship remains as strong as ever.
I am grateful to the many faculty members throughout the world who have
assigned this atlas to their students, whether in its original English or in one of
its translated forms that now counts 12 languages. I have received many
compliments and constructive suggestions not only from faculty members but
also from students, and I tried to incorporate those ideas into this new edition.
One suggestion that I have resisted, however, was to change the order of the
chapters. Several faculty members have suggested a number of varied sequences
and they all made sense to me. However, I feel partial to and very comfortable
with the classical sequence that we adopted so many years ago; it is just as valid
and logical an arrangement as all the others that were suggested, and, in the final
analysis, I believe that instructors and students may use the chapters of the atlas
in a different sequence without harming the coherence of the material.
As with all of my textbooks, the Color Atlas and Text of Histology has been
written with the student in mind; thus, the material is complete but not esoteric. I
wish to help the student learn and enjoy histology, not be overwhelmed by it.
Furthermore, this book is designed not only for use in the laboratory but also as
preparation for both didactic and practical examinations. Although I have
attempted to be accurate and complete, I know that errors and omissions may
have escaped my attention. Therefore, I welcome criticisms, suggestions, and
comments that could help improve this atlas; please address them to
[email protected]
Leslie P. Gartner
2
