Table Of ContentCANCER AND DIET
CANCERA NDD IET
WITHF ACTSA NDO BSERVATIONS
oN RELATESDu BJEcTs
By
r"
FREDERICK LH.O FFMAN,LL. D.
ThBei ochRemeisceaFalor� tct;hi ootfnh Fer anIknlsitni tute
Philadelphia
BALTIMORE
THE WILLIAMS& WILKINS COMPANY
1937
352489
CoPYRIGH1T9,3 7
THEW ILLIAMSW ILKINCSo MPANY
&
of
Madei nt heU nitSetda teAsme rica
PublishJeadn uar1y9,3 7
COMPOASNEDPD R INTEADT T HE
WAVERLPYR ESSIN,C .
THE WILIALM&SF W OIRL KCIONMSP ANY
BALTIMOMRnE.,, S .AU ..
DEDICATED TO
MR. SAMUEL S.F ELS
OF PmLADELPmA
IN GRATEFUL APPRECIATION
OF ms ENLIGHTENED INTEREST AND ENCOURAGEMENT
IN THE STUDY OF THE DIETARY ASPECTSO F THE CANCER PROBLEM,
AND ALSO TO
DR. ELLICEM cDONALD
FORms WHOLE-HEARTED CO PERATION AND ASSISTANCE
O
IN llAKING THE PUBLICATINO OFT mS WORK POSSIBLE.
PUBLISHER'S PREFACE
Comparoifts holeni st-pplraicocenbed os o okfss e vesroarmltu ss, t
itfh ceo mpairosef ar ni nquitruironnfmg i nbde,e xtrepmuezlzyl ing.
Sometail maersbg oeob ke aarp sr iaccet ulaelslsy t thhacath na rged
foars malolneerI. ng enetrhaeslre ee tmosb ea l acokfu niformity
betweenc hparraigncepdedh yseinctailt y.
Indetehrdee latiboentswheiepna npsdri mizaceye b es et daosw n
beisnodg i vetrhsaseti ze as oafp rciircqsieu t ievtraeil oune Tloeos s.
many modfiafcyitenongrti sent r op ermais tta rbellea tioOnnseh ip.
boohka asp otenmtairakolef1 t 0 0,0c0 op;ia ensotohf5e 0r0 T.h uisn
thoen cea s1e00 ,0c0 ooperpauttoartsi vely ttheaenk tee sr;epp arrit in
naturtahleclioyrn trimbauybt eip orno portlieotsnhsaa tinefo l nyl y
50j0io ni n.Or a gatihnce,o osftc omposition ovnabero kio es widely:
mayc omsto re atnhoatnth oce orm poesveet,nh ouigthh a osn lhya lf
asm anpya ges.
Stioltlhf earc tuonrsse,e nu nagnude sesnatbielnreI. ,n t hcea se
oft hbioso fko r inasl tiapsnrtci oecf$,e 5 .i0sn0 om orteh ahna loff
thper ijcsuet ibfiyei dtc so .s Tthipsr ihcaebs e emna dpeo ssbiyba l e
genersouubsv enmtaidwoein t,ah v ietwog ivitnhge basow oikda e
distribpuotsisoiTnbh lbeaeo s.o ki npi asr,tg ,it foeta v epruyr sceh.ra
THE PUBLISHERS.
vii
PREFACE
Eariln1y 9 3wh1e nw aIrs e acthhieenn god fm ye xtensdteuoddf y
thcea ncdearta an odb servcaotliloiennccs to endn ewcittimhyoS na n
FrancCiasnccoSe urr vmeyy , thoruegghatrscd ainnccgea ru sation,
treatamnednp tr evenbteicoacnmo en centurpaottnhe dedi etary
aspeocftt hsde i setaows hei Ich ha pdr evigoiuvsoelnnyli yn cidental
consideIrh aatvrieeo fne.rt eomn yrc eem aorntk hspi hsa osfce a ncer
reseasa rscefhto ritnmh y C ancMeorr taTlhirtoyu gthhoWeuo tr ld,
19,1m 5ya ddroenCs asn caenrCd i vilirzeaabtdei fotonhr Beee lgian
CancCeorn gr1e9s2ms3y,a, d droents hsCe a usaotfCi aonncd eerl ivered
beftohrAeem eriAcsasno cifoartC iaonncR eers eaBrucffha,,1l 9o24,
CancienNr a tiRvaec e1s9,2C 6a,n cienMr e xic1o9,2 C7a,n cer and
OvernutHreiatlCitoohnn g,or fets hRseo yIanls toiftP uubtHleei acl th,
GhenBte,l gi1u29m,7e, t .c tIh ereifnocrleiu ndm eydE ighStahn
FrancCiasnccRoee rp osrutcd ha tah aaadsv aIi laattb htleie mu en der
thtei tClaen cienRr e lattoiD oinea tn Ndu triwthiiocinhne , x tended
forcmo,n sttihtseue tceossne dc toifto hnwi osr k.
Thufosr t wenyteyao rrms o rteh,se u ebcjotfd iheatrs e cemiyv ed
attenctulmiinoant iinnagfi xedde termitnoia ntiitioindna u tceeo urse
ano rigsitnuabdlay s oende xtenfdaecrdte sg arldiivncigan ngcp ear
tieanntdos f c ourtshreee quinruemdbo efrn oncancceornoturso ls.
Thmee thoda dfiorpsittnce odnn ecwtiitmohynS aFnr ancCiasnccoe r
Surv1e9y2,4 h-a2yd5i ,e lfdaeipdrr loym irseisnubglu Itts s o orne a
liztehdaa mt o rues eful sthuadvtyeoh awvfoeoui rlts dso olbej ective
thaes certaoiftn hmaeec nttdu iaelt eaxrpye rioefcn acnecpsea tri ents
collbeycs tpeedcr ieaslea asrscihso tpaenrtaostnt i hnbega soifds e finite
instructions.
In1 913t hoeu tlfooosrku cahp reocjste emfeafdrr oemn couraging
budtu ritnhegea rplayro tft hwei ntoeftr h ayte ahre lcpa mteom e
froamnu nexpescotueer.Mdc r S.a muSe.Fl e losfP hiladewlhpoh ia
harde quessotmoeefd cmayn pcuebrl icatiotnhsde e esxtiporr ee ssed
disctuhsseis t uwaittimhoe an,n lda taegrr eteofid n antchneee cessary
fielodp eraotfsi uocnahss tuadsyI h adi nm indM.r. F elhsaf so r
many yteaakraesnni ntelalnidcg oennstt riunctteiirvnece se tn cer
reseapracrhtr,il cwyuli atrhe ferteogn acseta rniidc n tesctainncaelr s,
thediira gntorseiast,cma eunstaa,tn ipdoo ns spirbelvee .n ttiIho enre-
ix
PREFACE
X
forsue bmittoht iemadt entaptreiocvjfteoa rne xtensdteuoddfty h e
dietaasrpyeo cftt hsce a ncperro bwlhecimhs ,uj ebcttom odifications
suggebsyht iemwd,a a sd odp.tI ea geretdod evomtueco hfm yt ime
tot hsebu jted curialn ogn cgo ntemptlrtaiotpE eudr oapneNd o rth
ernMr(1i9c)3aa,2 n tdh per esweonritkts h ree lstuD.u ritnhgji usor
neIy mmeatn oyft hoeu tstaanudtihnogor nic tainecasne ndru trition
inG reBarti taanidon nt hCeo ntiwnietwnhht o Imd iscutshdseee d
taiolfms yp rojescttuoedndyt hbea soifms y q uestiwohninIca hi re
habdr ought wMiytj ho umrheno.ew ye,wv aelsri ,m ittoEe ndg land,
ScotlHaonldlG,ae nrdm,,a S nwyitzeSrplaaainnntdd h ,Fe r enpcohs ses
sioonfNso rtMhr iwchae Irm ea daeb risetfuo dfty h dei etcaursyt oms
oft hnea tpiovpeu lations.
Onm yr etIus rtna rtthweeod r iknP hiladaetsl epvhehiroaas lp itals,
gradually myefi xetleodnp deirnagtt oiB oonsst oSntL,.o uiSsa,n
FrancSiasAncn ot,o anniodot hpearr otfTs e xaIsw .a tched the re
sulctasr efaunlallyyt,sh ifienr gs t thcoaussteahsne,tdn h see cond,
wheInf etlhtta hti en trcionnssiicos ftt hedena ctjysau t itfiheaeds sump
tiotnh atthn eu mboefcr a sweasss u fficifeoanrc t o mplaentaeli yns is
almla ttoefdr est aIintl h.me e antIih maerd e aedx hausmtainvye ly
standwaorrdko snd ieatn ndu triatnitdor ne,a otnib sieosc hemistry
anpdh ysitoolm oagksyeu roefa s ousncdi ebnatcikfigcr footurhn ed
finaclo nsidoeftr hadeta itcoaon l l.e catIme pdlisfiuecsdht udies with
persionntaelr wviitemhwa nsay u thoarnibdty iw eosr wlidd ceo rre
spondoennd ceeb atqaubelset iAolonlfs t .h owsheo Ima pproached
on stuhebecj t mgeat vheew ihroh leea rstuepdpa onrmdta nvya luable
suggeswthiiocnhs imnactreeratishaepeldr l ayc vtailcouaftel h set udy
asi tfi naldleyv elaonpades sd e fto ritnwh h afto l.l ows
Theq uestiomnentahiorde afdotorhp petr eeds ent ipstu hrep ose
resoufl tm suicmhie lxapre riinoe tnhcfieeer l odfms e disctaalt istical
reseaIrtfc ahsl.hl osor fbt e ifnugls layt isfiantc htacoter rytd aiient ary
itewmesra ec cideonmtiatdltuleceydh ietfloty hf ea ct Ia tdhoaptt ed
fomry g uidatnhdceie e tsatrayt iasstt aibcusli antt herede poornt
Vitamoiftn hsBe r itMiisnhi sotfHr eya ltBhu.tt hoem issairoen s
nootfs eriimopuosr taannccdae en a sbieal lyl ofwoerOd.n t hweh ole
three suolftt hmsee thaordse ot horoughlyt hcaIoft ne sseiulsr tee nt
themya yb ea cceptecdo nwfiidtehn ce.
OrigiInh aalcdlo yn tempolnlaaytd eedt asitlueoddfty h vei tamin
aspeocftt h per oblseumb,s equeennltalrtygoie ndc lnuedaera llyl
thoer gaanniidcn orgcaonmipco uofnp drsa citmipcoarlt Iannd cies.
cussing otroe tchhenriiwncivasolsel c vieedqn uteisfitIchi aovqneus o ted
PREFACE xi
atl engtthrhee coganuitsheodrr aittihteehsrar ne luyp omny o wn
impermfeetchtoo fid nst erprfeoItra a mtn ieointa,hb eiro chneomri st
af oocdh emainscdta nnot tshpeewraiektfa hou rteh ourpiottnhy e se
aspeocftt hsme a npyr oblaenmdqs u estuinodncesor n sideIr ation.
havhea d gtrheeaa dtv anotffa rgeeq duiesnctu wsistiDhor nE.sl lice
McDonaDlidr,e coftt ohriL sa boraatnodr ym,oa fhn iyts e chnical
assaintsstT.h e,tn oIo ,w maossf to rtuinnma ytr ee seaasrscihs tants
whoc olltehcqteue eds tiofnrnocamai nrcpeeasrt iaenncdt osn tirno ls
diffepraernottfts h ceo untTrhywe.o rkP hiinl adwealdspo hniea by
MrsF.r anScteasor fVk e ntnNo.Jr .a,, n bdy m yd aughMtiesVrsi, r
ginHioaff mawnh,oa lscoo lleqcuteestdi oinnBn oasitraoennsdS an
Franccoi.Ts hew orikns outhernw asdT oenxbeay sM isLsu cille
StuaorfSt a Ann townhiiotl,he we o riknS tL.o uwiasds o nbeyM iss
MarWyo rroafKl ilr kwMoiosds,o Tuhrceio .n tcraosilenS s a Fnr an
ciswceorc eo llebcyMt rseV.di rgRiinnigaA. l l ttahbeu laatnido ns
calculoafct oiuonntsrl aetasenssd r atwieorse doMniesN sob rya
Powesltla,t iasntdmi actihaenm aetmipclioabynyte hdLi sa boratory.
Manoyt hteerc hnqiuceasltm iooronersl ebsesy omnydf uulnld er
stanIdh ianvgde i scuwsistDehrd S. t anRleeiym aonftn h Lea nkenau
HospiPthaill,a deTlhpuhIshi aav.te r iteogd u amryds ealgfa inst
persboinqaausli ctoem mionwn o rokft hkiis.n dFinaIla lmuy n,d er
sincoebrlei gtaotm iyso encsr eMtiasArsgy n,Le esn nwohnoh, a psr e
partehdme a nuscfrotirhp petr inatneadri dmeedi nc ountwlaeyissns
thhea ndloiftn hlgea ragmeo uonfdt a taan odb servaastw ieolnls ,
as
int hper eparoaftt hiieon nd ex.
Ith abd eemnyi ntenhtaisdop nal,ci em itpaetrimointtsoht aevde,
enlaurpgoetndh hei stodreivcealloo pfmm oednetdr ine tparrayc tices
ore atciunsgt boumttsh ,Ii h sa vhea tdo o misti ntcode o stbuhejec t
justwiocuehl adv mea tereixatlelnyd edo ftt hhbeeo osakil zree ady
growtnoa lmofsotr bipdrdoipnogr BtuitoI cn asn.n oomtia tv ery
brireeff erteotn hcdeei etaanrdgy a stronoobmsiecravilan Bt uirons
tonA'nsa toomfMy e lancfihrospltuy b,l iisn1h e6d2 B1u.r tionn ,
discucsussitnoogfdm is,er teferst otb hrieimm eeflnyrs aen ignde i etary
pracatmiocnteghsv e a ripoeuospo lfte hosel adn nde wwo rolbds,e rving
witrhe gatroAd m ertihcaat :
InA meriicnma a nyp lactehse birre aidsr oottsh,em iera pta lmiptionsa,s ,
potateote.cs,a,n d sfurcuhi tTsh.e rbee o ft hemt oot hafta miliarly drink
salt seaa-llt whaetlieirrv e easrt,a wm eatg,r asasn,dt hawti tdhe light. With
somefi,s, hs erpesnptisd,;ea rnsdi nd iveprlsa ctehsee ya mta n'flse srha wa nd
roasteevdet,nh Eem perMoert azuhmiam seIlnfs .o mceo asatgsa,io nn,et r ee
xii PREFACE
yieltdhse mc oco-nmuetasat,n dd rinkfi,r ef,u ealp,p arweilth hi lse avoeisl,,
vinegarc,o vefrohr o useetsc,a. n,dy etth emseen g,o innagk efde,e dcionagr se,
livceo mmonalnyh undryeeda rasr,se e ldoormn evesri cakl;wl h icdhi eotu r
physician forbid.
Thufisn difnaguw littd hi ethaarbyii nsto snt e wa ntdh sea mceo n
clusaipopnlt iofe osom do dificaotrdi eopnasr ftruortmeh sne a tural
foromff oocdo nsumpTtoit ohno.s ew iwsthhopo u rstuhceeh anges
in dietparrayc tIic caensnt,oo stot rornegcloym mtehrneed a doifn g
thviosl uomfee x ceedingloyb sienrtvearteisotnisn.g
Ith aadl bseoe mnyi ntenttohi aovbner ouignhtttho de i scutshsei on
extreimnetleyr oebssteirnvgoa ndt iiaeomtno snt ghE en glliasbho uring
clasatst ehesen odft heei ghtceeennttcuhor nyt,a iinanm eadg nificent
treaitnti hsreve oel uomneT sh eS taotfte h Peo obry,S iFrr ederic
Morton Eden1,7 9LT7oh.ni wdsoo rnik,so noef t hger eaotfe st
British ecoannodmt ihficer sictnlw ahsisctihhsc eus eb cjotf diet
recesitvaetsi asntdi cparlca octnisciadleT rhaebt oioouknn,.f ortu
natedloyen,so lte nidt steocl ofn venaibebnrte vainadt imobunes t
consulitne dot rhieg fionarav la satm ouonfut s eofbusle rsv.a tion
Iti nclfuoderex sa mpelxet,e nrdeemdao rnkp so taatsoae s st aple
artoifcf loeoi dn,c luadq iunogt aftriotomhn Re e poorftt h Beo aorfd
Agricu"ltthuparotet atanodew sa taelro wniet,ch o mmsoan lcta,n
nourischo mmpeln.e "tT ehleyarreee x tenodbesde rvoantt ihoen s
diffevraernitoe ftb ireeesaa dt aettn h tei me, ibnacrllbuerdyei andg
eatienGn l oucoeasbttr eerea,ad t ienSn c otalnatdnh dne o rtphaerrtn
ofE nglapnadr,t iciunYl oarrklsysh aigrboer ,e uasde idnt hEea st
Indiaenscd,o rbnr euasdei dnA meriTchaii.sfs o llboywe exdt ended
observoantt ihodeni se taorfAi meesr iNceagnr douersi tnhgse l ave
pericoodn,c ewrhniiicnithgss a i"dT:h maetnm ayli vea,nb de s trong
tol ab,ow uirtliht tolrne oa nimfoaoldi ,se vinbcyte hdfie e lnde groes
int hMei ddsltea otfNe osr Atmhe riwchaoa, ra enh ealatnhhdya rdy
racoefp eo;pa lnewd holsaeb oiuscr o nstaannsdto ,m etsiemveesr e,
althotuhgeahyrf ee adl most oennv teigreet.al"by l es
Thfeo regroeimnaagrr kaesm plibfiyee xdp eriamneodnb tsse rvations
onfl ouarnb dr edaedl ivbeyDr reI.dr vtionaC g o mmiotftt heHeeo use
ofC ommonFsi.n atlhleyar reoe b servoantd iroinnskh ianbgi ts,
particbueleaarlr,sel t,yo a untpd o rtdeirs,p ropotrott higeoe nnaetrea l
famibluyd geIt q.u otthefe o lloqwuianisgnt ta tem"etnhtei:rs e
hardall ayb oumrainon,fag n y acwchoautnetv edro,en oswtt h hoi nk
itn ecestsoia nrdyu hligmes eevlfe,dr ayy i,na certqauiann toift y
mallti quaonifrdt ; a xaetad n,ty i mwei,td hr intkoion gm huetc hhi,n ks
itas ufficiaennbdty n, o m eanasnu nbecoampionlgfo,ogh ryi mself,
