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Liron Pantanowitz, MD u
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Juan Xing, MD
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This is the first atlas dedicated to touch preparation cytopathology. Written by established pathologists who P r E Pa r at i o n
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are at the cutting edge of this minimally-invasive practice, the Atlas of Touch Preparation Cytopathology i
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presents a comprehensive overview and visual reference guide to the diagnostic applications of touch
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preparations. This visually-stunning book reviews touch preparations corresponding to all major body systems
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and includes chapters on specimen handling and processing, intraoperative use during frozen sections, as well
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as on ancillary testing using touch preps. While most cytopathology atlases have images of smears and fluids, t c y t o Pat h o L o g y
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they have very little discussion of touch preparations making this volume a one-of-a-kind resource.
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The authors, using many picturesque examples in the text, not only include detailed visual and textual t
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discussion of touch preparations but also provide comparative presentations to facilitate correlation with
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histopathology, FNA smears and ancillary test results. This total coverage illuminates key findings and
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important considerations of this technique that pathologists can learn from. Written with the practicing o
pathologist in mind, the Atlas of Touch Preparation Cytopathology is an invaluable book in today’s pathology g
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practice where there is increasing utilization of small biopsies that can benefit from intraprocedural evaluation
and assessment to maximize diagnostic yield.
Key Features: P
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n Covers various methods of touch preparation and addresses measures to t
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avoid pitfalls. n
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n Includes techniques that can serve as helpful tricks during intraprocedural
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evaluation of small biopsies and at the time of frozen section.
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n Comprehensive coverage of different body systems that are typically sampled with X L i r o n Pa n ta n o w i t z
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small biopsies and amenable to touch preparations. n
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n Contains over 500 touch preparation images and includes corresponding •
M J u a n X i n g
histopathologic figures and ancillary studies.
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Shelving Category: o S a r a E . M o n a c o
Pathology
An Imprint of Springer Publishing
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Atlas of Touch Preparation Cytopathology
Atlas of Touch Preparation Cytopathology
Liron Pantanowitz, MD
Professor of Pathology and Biomedical Informatics
Director of Cytopathology
UPMC Shadyside
Director of Pathology Informatics Fellowship Program
Director of the Pathology Informatics Division
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
Juan Xing, MD
Assistant Professor of Pathology
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
Sara E. Monaco, MD
Associate Professor of Pathology
Director of Cytopathology Fellowship Program
Director of Fine Needle Aspiration Clinic
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
An Imprint of Springer Publishing
Visit our website at www.demosmedical.com
ISBN: 9781620700686
ebook ISBN: 9781617052378
Acquisitions Editor: David D’Addona
Compositor: diacriTech
Copyright © 2018 Springer Publishing Company.
Demos Medical Publishing is an imprint of Springer Publishing Company, LLC.
All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in
any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the
publisher.
Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our under-
standing of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information
in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and
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Library of Congress Cataloging-in-Publication Data
Names: Pantanowitz, Liron, author. | Xing, Juan (Of University of Pittsburgh
Medical Center (2003- )), author. | Monaco, Sara E., author.s
Title: Atlas of touch preparation cytopathology / Liron Pantanowitz, Juan Xing, Sara E. Monaco.
Description: New York : Demos, [2018] | Includes bibliographical references and index.
Identifiers: LCCN 2017017714| ISBN 9781620700686 | ISBN 9781617052378 (e-book)
Subjects: | MESH: Cytodiagnosis–methods | Histocytological Preparation
Techniques–methods | Atlases
Classification: LCC RB43 | NLM QY 17 | DDC 616.07/582—dc23 LC record available at https://lccn.loc.gov/2017017714
Contact us to receive discount rates on bulk purchases.
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Printed in the United States of America by Bang Printing.
17 18 19 20 21 / 5 4 3 2 1
To Heidi, Joshua & Maya for their support and giving me the time to write this book.
Liron Pantanowitz
To my lovely husband Guodong and our two amazing daughters, Catherine and Sarah, for their
unconditional love and support.
Juan Xing
To my parents, husband, and children (Eddie, Julia, and Nicholas) for their endless
support and love.
Sara E. Monaco
Contents
Contributors ix 6. Hematopathology 83
Preface xi Liron Pantanowitz
Share Atlas of Touch Preparation Cytopathology Introduction 83
Normal 84
1. Introduction 1 Benign Entities 90
Sara E. Monaco and Liron Pantanowitz Malignant Entities 98
Background 1
7. Genitourinary System 133
Accuracy and Performance 6
6 Anil V. Parwani and Liron Pantanowitz
Advantages and Disadvantages
Introduction 133
Billing 7
Normal 133
Conclusion 7
Benign and Malignant Lesions 141
2. Preparation Techniques 9 Testis 146
Liron Pantanowitz Tumors of the Penis 159
Introduction 9
8. Pancreatobiliary, Liver, and
Slide Preparation 10
Gastrointestinal Tract 161
Fixation and Staining 14
Reetesh K. Pai
Problems and Pitfalls 14
Introduction 161
3. Intraoperative Cytology 19 Normal 161
Liron Pantanowitz and Juan Xing Benign Entities 165
Malignant Entities 166
Introduction 19
Primary Tumors of the Liver 175
Imprint Technique 19
21
Fixation and Staining Methods 9. Head and Neck 177
Suitable Samples 23 Juan Xing and Deborah J. Chute
Unsuitable Samples 29
Introduction 177
Diagnostic Errors 30
Normal 177
Benign Entities 179
4. Gynecological System 33
Malignant Entities 184
Zaibo Li and Chengquan Zhao
Introduction 33 10. Bone and Soft Tissue 195
Normal 33 Liron Pantanowitz
Benign Entities 33 Introduction 195
Malignant Entities 37 Bone Tissue 195
Soft Tissue 210
5. Respiratory System 49
Sara E. Monaco 11. Central Nervous System 243
Julia Kofler
Introduction 49
Normal 49 Introduction 243
Benign Entities 58 Sellar Region 243
Malignant Entities 63
vii
viii Contents
Extra-Axial Lesions 256 13. Ancillary Testing 291
Intra-Axial Lesions 263 Sara E. Monaco
12. Mediastinum, Retroperitoneum, and Introduction 291
Adrenal Glands 275 Material for Ancillary Testing 291
Juan Xing Types of Ancillary Testing 295
Pitfalls of Ancillary Testing 302
Introduction 275
Normal 275
Index 305
Benign Entities 277
Malignant Entities 282
Contributors
Deborah J. Chute, MD Anil V. Parwani, MD, PhD
Staff Pathologist Professor of Pathology
Assistant Professor of Pathology Vice Chair of Anatomic Pathology
RJ-Tomsich Institute of Pathology and Director of Pathology Informatics
Laboratory Medicine The Ohio State University Wexner Medical Center
Cleveland Clinic Columbus, Ohio
Cleveland, Ohio
Chengquan Zhao, MD
Julia Kofler, MD Professor of Pathology
Assistant Professor of Pathology Codirector of Cytopathology and Director of Fine
University of Pittsburgh Medical Center Needle Aspiration at Magee-Women’s Hospital,
Pittsburgh, Pennsylvania and Chief of Pathology, UPMC-China Enterprise
University of Pittsburgh Medical Center
Zaibo Li, MD, PhD Pittsburgh, Pennsylvania
Assistant Professor of Pathology
The Ohio State University Wexner Medical Center
Columbus, Ohio
Reetesh K. Pai, MD
Associate Professor of Pathology
Director of the Gastrointestinal Pathology
Center of Excellence
Director of the Gastrointestinal Pathology Fellowship
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
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