Table Of Content

AAnnttiiffuunnggaall PPhhaarrmmaaccoollooggyy Deborah Fox, Ph.D. Children’s Hospital 3219 RIC 504-896-2766 [email protected] Special thanks to: John Perfect, MD Andy Alspaugh, MD Sevtap Arikan, MD John Rex, MD www.doctorfungus.org Objectives • To recognize the clinical significance of fungal infections • To identify the antifungal agents and their mechanisms of action • To evaluate potential antifungal drug interactions and toxicities • To differentiate the mechanisms of antifungal drug resistance LLeeccttuurree oouuttlliinnee • Clinical significance of fungal infection • Fungal cell structure and targets • Antifungal agents and mechanism of action • Antifungal drug interactions & nephrotoxicity • Mechanisms of antifungal resistance • Summary MMyyccoollooggyy RReessoouurrcceess • http://www.doctorfungus.org • http://mycology.adelaide.edu.au/mycoses • http://mycology.cornell.edu/ • http://www.mycology.net/ LLeeccttuurree oouuttlliinnee • Clinical significance of fungal infection • Fungal cell structure and targets • Antifungal agents and mechanism of action • Antifungal drug interactions & nephrotoxicity • Mechanisms of antifungal resistance • Summary MMeeddiiccaall PPrroobblleemmss CCaauusseedd bbyy FFuunnggii 1) Allergic disease 2) “Mushroom” poisoning 3) Mycotoxins Secondary metabolites --many have industrial uses --Fusarium mycotoxin -- USSR after WWII --A. flavus “aflatoxin” 4) Mycoses -- infection and resulting disease cause by fungi TThhee FFuunnggii 150 primary human fungal pathogens 100,000 Validly described species of fungi Fungi yet to be discovered -Kwon-Chung and Bennett, 1992 TThhee FFuunnggii 150 primary human fungal pathogens 100,000 Validly described species of fungi Fungi yet to be discovered -Kwon-Chung and Bennett, 1992 TThhee FFuunnggii 150 Candida, Aspergillus, primary human Crypto, Blasto, Histo, Cocci, Dermatophytes fungal pathogens 100,000 Validly described species of fungi Fungi yet to be discovered -Kwon-Chung and Bennett, 1992

Description:

Allylamines, morpholines • Mechanism: block ergosterol synthesis via inhibition of squalene epoxidase (allylamines), sterol reductase and isomerase activity

Antifungal Pharmacology PDF

67 Pages·2009·7.58 MB·English

by Deborah Fox

Checking for file health...

Save to my drive

Quick download

Download

Download Antifungal Pharmacology PDF Free - Full Version

by Deborah Fox| 2009| 67 pages| 7.58| English

Download Antifungal Pharmacology by Deborah Fox in PDF format completely FREE. No registration required, no payment needed. Get instant access to this valuable resource on PDFdrive.to!

Free Download PDF

About Antifungal Pharmacology

Allylamines, morpholines • Mechanism: block ergosterol synthesis via inhibition of squalene epoxidase (allylamines), sterol reductase and isomerase activity

Detailed Information

Author:	Deborah Fox
Publication Year:	2009
Pages:	67
Language:	English
File Size:	7.58
Format:	PDF
Price:	FREE

Download Free PDF

Safe & Secure Download - No registration required

Why Choose PDFdrive for Your Free Antifungal Pharmacology Download?

100% Free: No hidden fees or subscriptions required for one book every day.
No Registration: Immediate access is available without creating accounts for one book every day.
Safe and Secure: Clean downloads without malware or viruses
Multiple Formats: PDF, MOBI, Mpub,... optimized for all devices
Educational Resource: Supporting knowledge sharing and learning

Frequently Asked Questions

Is it really free to download Antifungal Pharmacology PDF?

Yes, on https://PDFdrive.to you can download Antifungal Pharmacology by Deborah Fox completely free. We don't require any payment, subscription, or registration to access this PDF file. For 3 books every day.

How can I read Antifungal Pharmacology on my mobile device?

After downloading Antifungal Pharmacology PDF, you can open it with any PDF reader app on your phone or tablet. We recommend using Adobe Acrobat Reader, Apple Books, or Google Play Books for the best reading experience.

Is this the full version of Antifungal Pharmacology?

Yes, this is the complete PDF version of Antifungal Pharmacology by Deborah Fox. You will be able to read the entire content as in the printed version without missing any pages.

Is it legal to download Antifungal Pharmacology PDF for free?

https://PDFdrive.to provides links to free educational resources available online. We do not store any files on our servers. Please be aware of copyright laws in your country before downloading.

The materials shared are intended for research, educational, and personal use in accordance with fair use principles.