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Medical Informatics Training Program Final Presentation March 30, 2005 Aligning Representations of Anatomical Knowledge SSoonnggmmaaoo ZZhhaanngg,, PPhh..DD.. MMeennttoorr:: OOlliivviieerr BBooddeennrreeiiddeerr,, MM..DD..,, PPhh..DD.. LLiisstteerr HHiillll NNaattiioonnaall CCeenntteerr ffoorr BBiioommeeddiiccaall CCoommmmuunniiccaattiioonnss BBeetthheessddaa,, MMaarryyllaanndd -- UUSSAA GGeenneerraall ffrraammeewwoorrkk (cid:139)(cid:139)CCoommppaarriissoonn aanndd eevvaalluuaattiioonn ooff ssttrruuccttuurreess aanndd rreeaassoonniinngg ppootteennttiiaallss iinn ddiiffffeerreenntt mmeeddiiccaall kknnoowwlleeddggee rreepprreesseennttaattiioonn ssyysstteemmss (cid:139)(cid:139)CCaassee ssttuuddyy:: (cid:122)(cid:122) FFoouunnddaattiioonnaall MMooddeell ooff AAnnaattoommyy ((FFMMAA)) (cid:132)(cid:132) FFrraammee--bbaasseedd ssttrruuccttuurree (cid:122)(cid:122) GGAALLEENN ccoommmmoonn rreeffeerreennccee mmooddeell ((GGAALLEENN)) (cid:132)(cid:132) DDeessccrriippttiioonn llooggiicc LLLiiisssttteeerrr HHHiiillllll NNNaaatttiiiooonnnaaalll CCCeeennnttteeerrr fffooorrr BBBiiiooommmeeedddiiicccaaalll CCCooommmmmmuuunnniiicccaaatttiiiooonnnsss 2 AAnn oovveerrvviieeww ooff oouurr aalliiggnnmmeenntt pprroojjeecctt Lexical similarity 1 : 1 Structural similarity Concepts Generating direct alignment 11::11 ccoonncceepptt mmaattcchh (cid:139)(cid:139) LLeexxiiccaall aalliiggnnmmeenntt FFMMAA:: FFiibbuullaarriiss tteerrttiiuuss ((ssyynnoonnyymm:: PPeerroonneeoouuss tteerrttiiuuss)) GGAALLEENN:: PPeerroonneeuuss TTeerrttiiuuss LLLiiisssttteeerrr HHHiiillllll NNNaaatttiiiooonnnaaalll CCCeeennnttteeerrr fffooorrr BBBiiiooommmeeedddiiicccaaalll CCCooommmmmmuuunnniiicccaaatttiiiooonnnsss 5 11::11 ccoonncceepptt mmaattcchh (cid:139)(cid:139) SSttrruuccttuurraall aalliiggnnmmeenntt:: sshhaarreedd hhiieerraarrcchhiiccaall rreellaattiioonnsshhiippss aammoonngg ccoonncceepptt FMA GALEN Muscle Muscle of leg of Leg is-a is-a Peroneous Fibularis Tertius tertius part-of has-part part-of has-part Muscle cell Leg Myocyte Leg LLLiiisssttteeerrr HHHiiillllll NNNaaatttiiiooonnnaaalll CCCeeennnttteeerrr fffooorrr BBBiiiooommmeeedddiiicccaaalll CCCooommmmmmuuunnniiicccaaatttiiiooonnnsss 6 Lexical similarity 1 : 1 Structural similarity Concepts Generating n : m Structural similarity direct alignment nn::mm ccoonncceepptt mmaattcchh FMA GALEN Proximal Middle Extremity free limb free limb Long Part segment segment Arm Thigh Forearm Leg Arm Thigh Forearm Leg Left Right Left Right Left Right Left Right arm arm thigh thigh forearm forearm leg leg LLLiiisssttteeerrr HHHiiillllll NNNaaatttiiiooonnnaaalll CCCeeennnttteeerrr fffooorrr BBBiiiooommmeeedddiiicccaaalll CCCooommmmmmuuunnniiicccaaatttiiiooonnnsss 8 Lexical similarity 1 : 1 Structural similarity Concepts Generating n : m Structural similarity direct alignment Relationships Structural similarity AAssssoocciiaattiivvee rreellaattiioonnsshhiipp mmaappppiinngg ppaatttteerrnnss FFrreeqquueennccyy FFMMAA GGAALLEENN ((NN == 44,,007700)) bbrraanncchh ooff iissBBrraanncchhOOff 331100 88%% mmeemmbbeerr ooff iiss--aa 4422 11%% nneerrvvee ssuuppppllyy ppaarrtt--ooff –– iissSSeerrvveeddBByy 1166 00..44%% ppaarrtt--ooff –– ccoonnttaaiinneedd iinn iissNNoonnPPaarrttiittiivveellyyCCoonnttaaiinneeddIInn 1100 00..2255%% ccoonnttaaiinneedd iinn bboouunnddssSSppaaccee –– iinnvveerrssee--iissaa 22 00..0055%% LLLiiisssttteeerrr HHHiiillllll NNNaaatttiiiooonnnaaalll CCCeeennnttteeerrr fffooorrr BBBiiiooommmeeedddiiicccaaalll CCCooommmmmmuuunnniiicccaaatttiiiooonnnsss 10

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Fibularis tertius Peroneous Tertius FMA GALEN. Generating direct alignment Concepts 1 : 1 n : m Structural similarity Lexical similarity Structural similarity.

Aligning Representations of Anatomical Knowledge PDF

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Fibularis tertius Peroneous Tertius FMA GALEN. Generating direct alignment Concepts 1 : 1 n : m Structural similarity Lexical similarity Structural similarity.

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Publication Year:	2006
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