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About Synaptic Dynamics: John D. Murray July 2011
The document summarizes key aspects of synaptic dynamics: 1) It presents a model for the synaptic gating variable S that gates synaptic current, and shows that S can saturate at high firing rates for receptors with slow time constants like NMDA receptors. 2) It describes how shunting inhibition has a divisive effect on membrane potential but a subtractive effect on firing rate. 3) It explains that NMDA receptors display voltage-dependent activation due to magnesium block, allowing them to act as coincidence detectors of pre-synaptic and post-synaptic activity.
Detailed Information
| Author: | ['John D. Murray'] |
|---|---|
| Publication Year: | 2011 |
| Pages: | 5 |
| Language: | English |
| Format: | |
| Price: | FREE |
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