Table Of Content“COMPARATIVE CLINICAL STUDY ON EFFECT OF
VAMANA FOLLOWED BY LEPA AND ONLY LEPA IN
YOUVANA PIDAKA (ACNE VULGARIS)”
– By –
Anil S. Managuli
Dissertation submitted to the
Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka.
In partial fulfillment
of the requirement for the degree of
Ayurveda Vachaspati
(Doctor of Medicine)
In
Panchakarma
Under the guidance of
Dr. Sanghamitra Patnaik
M.D. (Ayu)
Associate Professor & H. O. D.
Department of P.G. Studies in Panchakarma
Under the Co-guidance of
Dr. Anilkumar Baccha
M.D. (Ayu)
Asst. Professor
Department of Kayachikitsa
DEPARTMENT OF P.G. STUDIES IN PANCHAKARMA
N.K.J. AYURVEDIC MEDICAL COLLEGE &
P. G. RESEARCH CENTER, GUMPA, BIDAR – 585 403.
2009.
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,
BANGALORE, KARNATAKA.
DECLARATION BY THE CANDIDATE
I hereby declare that this dissertation entitled
“COMPARATIVE CLINICAL STUDY ON EFFECT OF
VAMANA FOLLOWED BY LEPA AND ONLY LEPA IN
YOUVANA PIDAKA (ACNE VULGARIS)” is a bonafide and
genuine research work carried out by me under the guidance of
Dr. Sanghamitra Patnaik Associate Professor Department of
M.D. (Ayu)
P.G. Studies in Panchakarma and under the co-guidance of
Dr. Anilkumar Baccha Asst. Professor, Department of
M.D.(Ayu).
Kayachikitsa N.K.J. Ayurvedic Medical College & P. G. Research
Center, Gumpa, Bidar.
Date : Signature of the Candidate
Place: BIDAR. (Anil S. Managuli)
DEPARTMENT OF POSTGRADUATE STUDIES IN
PANCHAKARMA
N.K.J.A.M.C., P.G. RESEARCH CENTER, BIDAR.
(Affiliated to Rajiv Gandhi University of Health Sciences,
Bangalore, Karnataka)
CERTIFICATE BY THE GUIDE
This is to certify that the dissertation entitled
“COMPARATIVE CLINICAL STUDY ON EFFECT OF
VAMANA FOLLOWED BY LEPA AND ONLY LEPA IN
YOUVANA PIDAKA (ACNE VULGARIS)” is a bonafide
research work done by the “Anil S. Managuli” in partial fulfillment of
the requirement for the degree of Ayurveda Vachaspati M. D. (Ayu)
Signature of the Guide
Date :
Dr. Sanghamitra Patnaik
Place: BIDAR. M.D. (Ayu)
Associate Professor
Dept. of P.G. Studies in Panchakarma
N.K.J.A.M.C., P.G. Research Center, Bidar.
DEPARTMENT OF POSTGRADUATE STUDIES IN
PANCHAKARMA
N.K.J.A.M.C., P.G. RESEARCH CENTER, BIDAR.
(Affiliated to Rajiv Gandhi University of Health Sciences,
Bangalore, Karnataka)
CERTIFICATE BY THE CO-GUIDE
This is to certify that the dissertation entitled
“COMPARATIVE CLINICAL STUDY ON EFFECT OF
VAMANA FOLLOWED BY LEPA AND ONLY LEPA IN
YOUVANA PIDAKA (ACNE VULGARIS)” is a bonafide
research work done by the “Anil S. Managuli” in partial fulfillment of
the requirement for the degree of Ayurveda Vachaspati M. D. (Ayu)
Signature of the Co-Guide
Date :
Dr. Anilkumar Baccha
Place: BIDAR.
M.D. (Ayu)
Asst. Professor,
Department of Kayachikitsa
N.K.J.A.M.C., P.G. Research Center, Bidar.
DEPARTMENT OF POSTGRADUATE STUDIES IN
PANCHAKARMA
N.K.J.A.M.C., P.G. RESEARCH CENTER, BIDAR.
(Affiliated to Rajiv Gandhi University of Health Sciences,
Bangalore, Karnataka)
ENDORSEMENT BY THE H.O.D. & PRINCIPAL
This is to certify that the dissertation entitled
“COMPARATIVE CLINICAL STUDY ON EFFECT OF
VAMANA FOLLOWED BY LEPA AND ONLY LEPA IN
YOUVANA PIDAKA (ACNE VULGARIS)” is a bonafide
research work done by the “Anil S. Managuli” under the guidance of
Dr. Sanghamitra Patnaik Associate Professor & H. O. D.
M.D. (Ayu)
Department of P.G. Studies in Panchakarma N. K. J. Ayurvedic
Medical College & P. G. Research Center, Gumpa, Bidar.
H. O. D. PRINCIPAL
Dr. Sanghamitra Patnaik Dr. K. V. L. N. Acharyulu
M.D. (Ayu) M.D. (Ayu)
Department of P.G. Studies Principal & Dean
in Panchakarma
N. K. J. Ayurvedic Medical College & P. G. Research Center, Bidar.
Date : Place: BIDAR.
COPY RIGHT
DECLARATION BY THE CANDIDATE
I hereby declare that the Rajiv Gandhi University of
Health Sciences, Bangalore, Karnataka shall have the rights to
preserve, use and disseminate this dissertation in print or electronic
format for academic / research purpose.
Date : Signature of the Candidate
Place: BIDAR.
(Anil S. Managuli)
©
Rajiv Gandhi University of Health Sciences,
Bangalore, Karnataka.
A
CKNOWLEDGEMENT
“L
ove is the only inspiration.” Along with the divine blessings of
Lord Manjunatheshwar and Lord Dhanwantari, this work carries some
memories to express gratitude and record some distinguished
personalities with whom I had inspired during the course of this thesis.
It is an inexplicable pleasure, sincere and respectful regards to
Pujya Shri. Shri. Siddharudha Mahaswamiji, Siddharudha Math,
Gumpa, Bidar.
My vocabulary falls short of suitable words to express my recondite
sense of indebtedness –
(cid:1) Dr. K. V. L. N. Acharuyulu Principal & Dean
M.D. (Ayu)
(cid:1) Dr. P. V. Sauvnur Vice-Principal
M.D. (Ayu)
(cid:1) Dr. V. S. Patil Medical Advisor
M.D. (Ayu)
(cid:1) Dr. Sanghamitra Patnaik, Guide & H. O. D.
M.D. (Ayu)
(cid:1) Dr. Anilkumar Bacha
M.D. (Ayu)
N. K. J. A. M. C., P. G. Research Center, Bidar.
It is beyond the reach of my language to inscribe the profound
respect and devotion towards affectionate to
(cid:1) Dr. Harini C. Asst. Prof. PG Dept. Of Panchakarma
M.D.(Ayu),
(cid:1) Dr. Manikrao Kulkarni Lecturer, PG Dept. Of Panchakarma
M.D.(Ayu),
(cid:1) Dr. Nagesh Gandagi, Lecturer, Dept. of Kayachikitsa
M.D. (Ayu)
(cid:1) Dr. Deepali Sherikar Lecturer, Dept. Of Kayachikitsa
M.D.(Ayu),
(cid:1) Dr. Sanjeev Kadalewad M.D.(Ayu), Lecturer, Dept. Of Kayachikitsa
(cid:1) Dr. Ratnakar L. V. Prof. & HOD PG Dept. Of Prasutitantra
M.S.(Ayu),
(cid:1) Dr. Bandeppa Sangolagi, Asst. Prof. Dept. of Rasashastra
M.D. (Ayu)
(cid:1) Dr. Praveen Shimpi Asst. Prof. Dept. of Rasashastra
M.D. (Ayu)
(cid:1) Dr. Chandrakant Halli Asst. Prof, PG Dept. of Shalyatantra
M.D. (Ayu)
(cid:1) Dr. Divyadarshan Shelly RMO & Lecturer Dept. of
M.D. (Ayu)
Shareera Rachana
N.K.J.A.M.C., & P.G. Research Center, Bidar.
I express my obligation and heartfelt thanks to my teachers
(cid:1) Dr. Anand Jabshetty Asst. Prof. BIMS, Bidar.
M.S. (Ortho)
(cid:1) Dr. Vijaykumar Kote Dermatologist, Asst. Prof. BIMS, Bidar.
M.D.DVD
(cid:1) Dr. Sipra Sasmal C.C.R.A.S., Bhuvaneshwar.
M.D. (Ayu)
(cid:1) Dr. Mallikarjun Malipatil Professor Dept. Of
M.Pharma., Ph. D.
Pharmacognosy, Karnataka College of Pharmacy
I acknowledge technical and non-technical staff members of our
institute who have helped me – Shri. Rajakumar Kadam, (Lib.) Smt.
Sakubai, Shri. Rajkumar, Shri. Kanteppa, Shri. Basavaraj, Smt.
Parvathi, Smt. Guramma, Smt. Padmavati, Mr. Jagadish, Mr. Santosh,
Shri. Mohan Reddy, at N. K. J. A. M. C., P. G. Research Center, Bidar.
I wish to express thanks to my friends, seniors, juniors & colleagues.
Special thanks to Dr. K.P. Namboothiri, Dr. Girish, Dr. Pradeep, Dr.
Gourish, Dr. Mahesh, Dr. Vivek, Dr. Prashant, Dr. Omprakash, Dr.
Siddharam, Dr. Santosh, Dr. Shankar, Dr. Satish, Dr. Jyoti Dr. Raju,
and Dr. Muralikrishna
As I recall my parents Shri. Shivaputra B. Managuli and Smt.
Sushila who advised me to enter in this noble profession. The truth dawns
on me that the language of words suffers very stringent limitation. I have
not been able to find words enough to express my sentiments, love,
respect and gratitude for them.
I must record the occasion to show love and gratitude towards my
younger brother Mr. Sunil & Shri. Umesh Patil & Smt. Sunita who
inspired and blessed me to achieve this milestone in my life along with
their timely help in many ways like moral support, financial assistance, etc.
I acknowledge my patients for their wholehearted consent to
participate in this clinical trial. I thank my patients who exhibited high level
of patience and subjected themselves for cooperating with me in every
stage of my clinical work.
Lastly I express my thanks to all the persons who have helped me
directly and indirectly with apologies for my inability to specify them
individually. I did this work as a partial fulfillment of Post graduation
degree, but dedicate to forthcoming researchers of Ayurveda.
DATE : (Anil S. Managuli)
PLACE : BIDAR.
A
BBREVIATIONS
(cid:2) AH – Ashtanga Hridaya
(cid:2) AS – Ashtanga Sangraha
(cid:2) CS – Charaka Samhita
(cid:2) BV – Bhavaprakasha
(cid:2) MN – Madhava Nidana
(cid:2) ShS – Sharangadhara Samhita
(cid:2) SS – Sushruta Samhita
(cid:2) YR – Yoga Ratnakara
(cid:2) AD – Arundatta
(cid:2) Gr – Group
(cid:2) BT – Before Treatment (Day 0)
(cid:2) AT – After treatment (Day 7)
(cid:2) FU1 – 1st Follow up (45 Days after treatment)
(cid:2) FU2 – 2nd Follow up (75 Days after treatment)
(cid:2) FU3 – 3rd Follow up (105 Days after treatment)
(cid:2) NI – No improvement
(cid:2) MiR – Mild relief
(cid:2) MoR – Moderate relief
(cid:2) MrR – Marked relief
(cid:2) CR – Complete relief
A
BSTRACT
Background and Objectives
Acne vulgaris is a chronic inflammatory disease of the
pilosebaceous units of the skin of certain body parts with formation of a
papules / pustules eruption commonly known as pimples. The classical
description of Youvana Pidaka resembles with this.
Objective of the present study was to evaluate and compare the
effect of Vamana with Lepa and only Lepa in Youvana Pidaka (Acne
vulgaris).
Methods
30 patients filling the inclusion criteria of Youvana Pidaka were
randomly selected and divided into 2 groups. In Gr. A the patients were
subjected for Vamana with Kritavedhana followed by Manjishta Madhu
Lepa. In Gr. B the patients were subjected for Manjishta Madhu Lepa.
Source of the data – Patients were selected from OPD and IPD of
PG Department of Panchakarma, N.K.J.A.M.C., P. G. Research Center,
Bidar.
Clinical signs and symptoms were given suitable self formulated
scores according to its severity. Patients were assessed based on pre and
post data gathered through pre-designed research proforma.
The results having ‘p’ value less than <0.05 was considered to be
statistically significant in this study.
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