lipofilling and prp for aesthetic rejuvenation facial

132 Pages·2017·6.82 MB·English

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Understanding and augmenting the lipograft
Joep C.N. Willemsen
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Formation and publication of this thesis was possible by generous
contribution from Bergman Clinics
Additional financial and technical support was contributed by:
University of Groningen (RUG)
Groningen University Institute for Drug Exploration (GUIDE)
Department of Plastic Surgery University Medical Center Groningen (UMCG)
Willemsen, J.C.N.
Lipofilling and PRP for Aesthetic Facial Rejuvenation: Understanding and augmenting the lipograft
ISBN: 978-94-034-0611-4 (printed version)
ISBN: 978-94-034-0610-7 (electronic version)
Layout: J.C.N. Willemsen and NCP B.V.
Printing: Iskamp printing B.V.
© J.C.N. Willemsen 2018
All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted
in any form or by any means, electronic, mechanical, by photocopying, recording, or otherwise, without
the written permission of the author, or, when appropriate, of the publisher of the publication.
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Lipofilling and PRP for Aesthetic
Facial Rejuvenation

Understanding and augmenting the lipograft

Proefschrift

ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken
en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op

woensdag 11 april 2018 om 12.45 uur

door

Joep Carlus Natasja Willemsen

geboren op 11 oktober 1984
te Zevenaar
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Promotores
Prof. dr. B. van der Lei
Prof. dr. M.C. Harmsen

Copromotor
Dr. H.P.J.D. Stevens

Beoordelingscommissie
Prof. dr. D. Ulrich
Prof. dr. R. van der Hulst
Prof. dr. R.A. Bank

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Paranimfen
Drs. E.J.P.M ten Dam
Drs. A.J.H. Engels
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TABLE OF
CONTENTS
Chapter 1 8
General introduction and outline of this thesis
Chapter 2 20
Lipofilling in MACS lifting enhances rejuvenation
Chapter 3 32
The effects of platelet rich plasma on recovery time and aesthetic outcome
in facial rejuvenation: preliminary retrospective observations
Chapter 4 44
The addition of PRP to facial lipofilling: a double-blind placebo-controlled
randomized trial
Chapter 5 62
The concentration depended effect of Platelet rich plasma on Adipose
Stem Cells in vitro
6
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Chapter 6 82
The power of fat and its adipose-derived stromal cells: emerging concepts
for fibrotic scar treatment
Chapter 7 108
General discussion and future perspectives
Chapter 8 118
Summary
Chapter 9 124
Addendum
7
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Chapter 1 - General introduction and outline of this thesis
I
GENERAL INTRODUCTION AND OUTLINE OF
THIS THESIS
1. JOEP C.N. WILLEMSEN
8
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