Table Of ContentDUNCAN & PRASSE’S
VETERINARY LABORATORY MEDICINE:
CLINICAL PATHOLOGY
Fifth Edition
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DUNCAN & PRASSE’S
VETERINARY LABORATORY MEDICINE:
CLINICAL PATHOLOGY
Fifth Edition
KENNETH S. LATIMER
A John Wiley & Sons, Inc., Publication
This edition first published 2011 © 2011 by John Wiley & Sons, Inc.
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Library of Congress Cataloging-in-Publication Data
Duncan & Prasse’s veterinary laboratory medicine : clinical pathology / [edited by] Kenneth S. Latimer. – 5th ed.
p. ; cm.
Duncan and Prasse’s veterinary laboratory medicine
Veterinary laboratory medicine
Rev. ed. of: Duncan & Prasse’s veterinary laboratory medicine / Kenneth S. Latimer, Edward a. Mahaffey,
Keith W. Prasse. 4th ed. 2003.
Includes bibliographical references and index.
ISBN 978-0-8138-2014-9 (hardcover : alk. paper) 1. Veterinary clinical pathology. I. Latimer,
Kenneth S. II. Duncan, J. Robert. III. Latimer, Kenneth S. Duncan & Prasse’s veterinary laboratory
medicine. IV. Title: Duncan and Prasse’s veterinary laboratory medicine. V. Title: Veterinary laboratory medicine.
[DNLM: 1. Pathology, Veterinary–Outlines. 2. Pathology, Clinical–Outlines. SF 772.6]
SF772.6.D86 2011
636.089'607–dc22
2010049553
A catalogue record for this book is available from the British Library.
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1 2011
TABLE OF CONTENTS
Contributing Authors vii
PrefACe ix
ACknowledgments xi
ChAPter 1. erythroCytes 3
ChAPter 2. leukoCytes 45
ChAPter 3. hemAtoPoietiC neoPlAsiA 83
ChAPter 4. hemostAsis 107
ChAPter 5. wAter, eleCtrolytes, And ACid bAse 145
ChAPter 6. Proteins, liPids, And CArbohydrAtes 173
ChAPter 7. liver 211
ChAPter 8. digestive system 231
ChAPter 9. urinAry system 253
ChAPter 10. musCle 283
ChAPter 11. endoCrine system 295
ChAPter 12. Cytology 331
ChAPter 13. generAting And interPreting test results: test vAlidity, QuAlity Control,
referenCe vAlues, And bAsiC ePidemiology 365
CAse studies 383
index 475
Companion website
This book is accompanied by a companion website:
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The website includes:
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v
CONTRIBUTING AUTHORS
Perry J. Bain, DVM, PhD Charles W. Brockus, DVM, PhD
Diplomate, American College of Veterinary Diplomate, American College of Veterinary
Pathologists Internal Medicine
Assistant Professor Diplomate, American College of Veterinary
Department of Biomedical Sciences Pathologists
Large Animal Hospital Charles River
Cummings School of Veterinary Medicine at Reno, NV 89511
Tufts University
North Grafton, MA 01536 Ellen W. Evans, DVM, PhD
Diplomate, American College of Veterinary
Holly S. Bender, DVM, PhD Pathologists
Diplomate, American College of Veterinary Senior Director, Immunotoxicology Center of
Pathologists Emphasis
Professor Pfizer, Inc.
Department of Veterinary Pathology Groton, CT 06340
College of Veterinary Medicine
Iowa State University Duncan C. Ferguson, VMD, PhD
Ames, IA 50011 Diplomate, American College of Veterinary
Internal Medicine
Dorothee Bienzle, DVM, MSc, PhD Diplomate, American College of Veterinary
Diplomate, American College of Veterinary Clinical Pharmacology
Pathologists Professor and Head
Professor and Canada Research Chair in Department of Veterinary Biosciences
Veterinary Pathology College of Veterinary Medicine
Department of Pathobiology University of Illinois at Urbana-Champaign
Ontario Veterinary College Urbana, IL 61802
University of Guelph
Guelph, Ontario, Canada N1G 2W1 Jeanne W. George, DVM, PhD
Diplomate, American College of Veterinary
Mary K. Boudreaux, DVM, PhD Pathologists
Professor Professor Emeritus
Department of Pathobiology Department of Pathology, Microbiology and
College of Veterinary Medicine Immunology
Auburn University, AL 36849 School of Veterinary Medicine
University of California-Davis
Denise I. Bounous, DVM, PhD Davis, CA 95616
Medical Technologist (American Society of
Clinical Pathologists)
Diplomate, American College of Veterinary
Pathologists
Group Director, Drug Safety Evaluation
Bristol-Myers Squibb
Princeton, NJ 08543
vii
viii CONTRIBUTING AUTHORS
Christopher R. Gregory, DVM, PhD Elizabeth A. Spangler, DVM, PhD
Medical Technologist (American Society of Diplomate, American College of Veterinary
Clinical Pathologists) Pathologists
Associate Research Scientist Diplomate, American College of Veterinary
Department of Small Animal Medicine Internal Medicine
College of Veterinary Medicine Assistant Professor
The University of Georgia Department of Pathobiology
Athens, GA 30602 College of Veterinary Medicine
Auburn University, AL 36849
Robert L. Hall, DVM, PhD
Diplomate, American College of Veterinary Heather L. Tarpley, DVM
Pathologists Diplomate, American College of Veterinary
Covance Laboratories, Inc. Pathologists
Madison, WI 53704 Chestatee Animal Hospital
Dahlonega, GA 30533
Margarethe Hoenig, Dr med vet, PhD
Professor Niraj K. Tripathi, BVScAH, MVSc, PhD
Department of Veterinary Clinical Medicine Diplomate, American College of Veterinary
College of Veterinary Medicine Pathologists
University of Illinois at Urbana-Champaign Covance Laboratories, Inc.
Urbana, IL 61802 Madison, WI 53704
Paula M. Krimer, DVM, DVSc Julie L. Webb, DVM
Diplomate, American College of Veterinary Diplomate, American College of Veterinary
Pathologists Pathologists
Assistant Professor Instructor
Athens Veterinary Diagnostic Laboratory Department of Pathobiological Sciences
College of Veterinary Medicine College of Veterinary Medicine
The University of Georgia University of Wisconsin
Athens, GA 30602 Madison, WI 53706
Kenneth S. Latimer, DVM, PhD Elizabeth G. Welles, DVM, PhD
Diplomate, American College of Veterinary Diplomate, American College of Veterinary
Pathologists Pathologists
Covance Laboratories, Inc. Professor
Vienna, VA 22182 Department of Pathobiology
and College of Veterinary Medicine
Professor Emeritus Auburn University
Department of Pathology Auburn, AL 36849
College of Veterinary Medicine
The University of Georgia Shanon M. Zabolotzky, DVM
Athens, GA 30602 Diplomate, American College of Veterinary
Pathologists
Pauline M. Rakich, DVM, PhD Clinical Pathologist
Diplomate, American College of Veterinary IDEXX Laboratories, Inc.
Pathologists West Sacramento, CA 95605
Professor
Athens Veterinary Diagnostic Laboratory
College of Veterinary Medicine
The University of Georgia
Athens, GA 30602
