Dr.Abd El Aziz Mohamed Mohamed Abd El Aziz

16 Pages·2016·0.43 MB·English

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Personal Data:
 Name: Abdel Aziz Mohammed Hussein.
 Nationality: Egyptian.
 Date of Birth: December 28, 1972.
 Place of Birth: Damas, MitGhamr, Dakahlia, Egypt.
 Address: ELamr Building, Masaken El-Shenaway, Mansoura, Egypt.

 Religion: Muslim.
 Martial Status: Married.
 Tel: Home: 050/9104268, Mobile: [phone]).
 Email : [email protected];[email protected]
 Website: www.mans.edu.eg

Qualifications:
Degree Major Year University Country Thesis Title
MB, B.Ch Medicine 1997 Mansoura Egypt -------------------
University
Msc thesis Medical 2004 Mansoura Egypt Role of L-arginine and
Physiology University Prostaglandin E1 in Renal
Ischemia/Reperfusion Injury in Rat
Kidneys.
PhD thesis Medical 2008 Mansoura Egypt Role of Epidermal Growth Factor
Physiology University and Erythropoietin in Renal
Ischemia/Reperfusion Injury in Rat
Kidneys

Positions:
Academic Positions Held:
1. 1/3/1998 to 28/2/1999: Rotating internship, Mansoura University Hospital.
2. 1/3/1999 to 6/6/1999: Primary health care physician in Mansoura health district,
Dakahlia Health Directorate, MOHP, Egypt.
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3. 6/1999 to 9/2004: Demonstrator of Physiology, Department of physiology, Faculty of
Medicine, Mansoura University.
4. 9/2004 to 8/2008: Assistant Lecturer of Physiology, Department of physiology,
Faculty of Medicine, Mansoura University.
5. 8/2008 to 11/2013: Lecturer of Physiology, Department of physiology, Faculty of
Medicine (accredited 2011), Mansoura University.
6. 11/2013 to date: Assistant professor of Physiology, Department of physiology,
Faculty of Medicine, Mansoura University.
7. Visiting Scientist In Department of Physiology and Biomedical Engineering,
Mayoclinic Rochester MN, USA, April 14, 2014- June 14, 2014.

Professional Positions Held:
1. Associate Editor of Bulletin of Egyptian Society for Physiological Sciences
(ESPS) from March 2013 – till now
2. Secretary of Egyptian Society for Physiological Sciences (ESPS) from March 2014
– till now

Administrative Positions Held:
1. Head of Research Projects and Prizes Committee , Mansoura Faculty of Medicine,
Mansoura University, Egypt
2. Head of the committee of online MCQ exams for postgraduate students ,
Mansoura Faculty of Medicine, Mansoura University, Egypt

Teaching Activities:
1. Teaching practical courses of Medical Physiology for medical undergraduate
students from 1999 till now
2. Teaching theoretical parts of physiology of nerve and muscle, biophysics and
cardiovascular system, pulmonary system, digestive system, central nervous
system, special senses, metabolism, endocrine and renal physiology for medical
undergraduate students from 2008 till now
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3. Teaching courses of medical physiology for the undergraduate students of nursing,
dentistry and pharmacy and public health institute from 2008 till now
4. Teaching courses of medical physiology for the undergraduate students of physical
therapy from 2013 till now
5. Author of E-course of Physiology of Special Senses funded by national E-learning
Center (NELC) (ICTP and SCU), Egypt.
http://mansvu.mans.edu.eg/site/index.php?page=ecourse&task=show&lang=ar.
http://www.tubey.net/viewFauyIUMbnWg.html
6. Teaching for undergraduate students of Manchester Mansoura Medical Program
(MMMP) (problem based learning program) and tutor in the program for more
than 7 years.
7. Sharing in putting exams for students of MMMP (written, MCQ and OSCE)
Training Courses:
1. Attending English Language course, Mansoura Faculty of Medicine, 2001.
2. Attending program for preparing the university teaching staff, Mansoura Faculty of
Education, 2001.
3. Attending Medical Statistics course, Mansoura Faculty of Medicine, 2007.
4. Attending Scientific & Research Methodology course, Mansoura Faculty of
Medicine, 2007.
5. Attending 6 FLDP workshops (2008) entitled;
a. Financial and law regulations of university (15 hours)
b. Effective presentation skills course (15 hours)
c. Teaching with technology (15 hours)
d. Effective teaching (15 hours)
e. Decision making & problems solving (15 hours)
f. Career ethics & rules (15 hours)
6. Attending 6 FLDP workshops (2009- 2013) entitled;
a. Financial and legal aspects of university (15 hours)
b. Standards of educational process (15 hours)
c. Credit hour system (15 hours)
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d. National and international competing Research projects (15 hours)
e. Research project management (15 hours)
f. Examination assessment and evaluation (15 hours)

Workshops:
1. Attending Workshop titled “Basic Techniques in Tissue Culture” organized by the
Research Medical Center, Alexandria Faculty of Medicine, 2008.
2. Attending Workshop titled “Trends and Challenges in Physiology Education:
Africa and the West 6th international congress of African association of
physiological science, Ismailia, Egypt, Sept, 2, 2012.
3. Attending Workshop titled “Basics of Molecular Biology, Mansoura, Egypt, Sept,
12-18, 2012.
4. Coordinator and speaker in the 1st international Workshop in “Basics of Molecular
Biology, Urology and Nephrology Center, Mansoura, Egypt, Sept, 21-27, 2013.

Research Activities:
Research grants:
1. Co-investigator in research project in Urology and Nephrology center, Mansoura
University entitled "Recoverability of renal function after relief of chronic
unilateral ureteric obstruction in solitary kidney". This work was funded by the
Science and Technology Development Fund (STDF), Egypt-grant no. 996., 2009
2. Co-investigator in research project in Urology and Nephrology center, Mansoura
University entitled "chromosomal instability and bladder cancer". This project
was funded through the Science and Technology Development Fund (STDF), Egypt-
grant no. 1080.2010
3. Co-investigator in research project in Urology and Nephrology center, Mansoura
University entitled "Renal protection against renal ischemia/reperfusion injury".
This project was funded by the Science and Technology Development Fund (STDF),
Egypt-grant no. 1146, 2011.
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4. Co-investigator in research project in Urology and Nephrology center, Mansoura
University entitled "stem cell and acute kidney injury". This project was funded by
the Science and Technology Development Fund (STDF). Egypt-grant no. 3948,2012
5. Supervisor of student's research project in Mansoura experimental research center
(MERC) entitled "pancreatic injury in renal ischemia/reperfusion injury: possible
role of oxidative stress". This project was funded by MERC, Mansoura University,
2012
6. Supervisor of student's research project in Mansoura experimental research center
(MERC) entitled "hepatic injury induced by ischemia/reperfusion injury: role of
nitric oxide". This project was funded by MERC, Mansoura University, 2012
7. Co-investigator in project of accreditation of molecular biology laboratory in
urology and nephrology center. This work is funded by Ministry of Higher Education,
Egypt, 2013
8. Co-investigator in project of Excellence Center in urology and nephrology center.
This work is funded by Ministry of Higher Education, Egypt. 2014
9. Supervisor of student's research project in Mansoura experimental research center
(MERC) entitled "Role of Toll Like receptors (TLRS) in Remote Limb ischemic
effect on renal ischemia/reperfusion Injury." This project was funded by MERC,
Mansoura University, 2014.
10. Supervisor of student's research project in Mansoura experimental research center
(MERC) entitled "Role of renin-angiotensin system in Remote Limb ischemic
effect on renal ischemia/reperfusion Injury". This project was funded by MERC,
Mansoura University, 2014
11. Visiting Scientist In Department of Physiology and Biomedical Engineering,
Mayoclinic Rochester MN, USA, April 14, 2014- June 14, 2014.
12. PI investigator for research project The effect of the muscular exercise and
ferulic acid on neuroprotective heat shock proteins in experimental Parkinson’s
model. This project was funded by STDF Egypt, grant NO.6896, 2015.

Publications (Google scholar site
https://scholar.google.com.eg/citations?user=EhtNaqMAAAAJ&hl=en
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1) International peer-reviewed journals:
1. Mahmoud IM, Hussein A.A., Sarhan ME, Awad AA, El Desoky I. Role of Combined
L-Arginine and Prostaglandin E 1 in Renal Ischemia-Reperfusion Injury. Nephron
Physiol. 2007;105(4):p57-65. Epub 2007 Mar 1.
2. Barakat N, Hussein AA, Abdel-Maboud M, El-Shair MA, Mostafa A, Abol-Enein H.
Ischemia/Reperfusion Injury in Renal Transplantation: The Role of Nitric Oxide in
Experimental Rat Model. BJU Int. 2010 Oct;106(8):1230-6. doi: 10.1111/j.1464-
410X.2010.09225.x.
3. Hussein Ael-A, Shokeir AA, Sarhan ME, El-Menabawy FR, Abd-Elmoneim HA, El-
Nashar EM, Barakat NM Effects of combined erythropoietin and epidermal growth
factor on renal ischaemia/reperfusion injury: a randomized experimental controlled
study. BJU Int. 2011 Jan;107(2):323-8. doi: 10.1111/j.1464-410X.2010.09328.x.
4. Mahmoud Gabr, Abdel-aziz Hussein, Iman Sherif, Sousou Ali & Hoda Mohamed.
Renal ischemia /reperfusion injury in type II DM: Possible role of proinflammatory
cytokines, apoptosis, and nitric oxide. Journal of Physiology and Pathophysiology
2011; 2(1): 6-17.
5. Hussein Ael-A, Omar NM, Sakr H, Elsamanoudy AZ, Shaheen D. Modulation of
Metabolic & Cardiac Dysfunctions by Insulin Sensitizers and Angiotensin Receptor
Blocker in Rat Model of Type 2 Diabetes Mellitus. Can J Physiol Pharmacol. 2011
Mar;89(3):216-26. doi: 10.1139/Y11-012.
6. Shokeir AA, Barakat N, Hussein AA, Awadalla A, Abdel-Aziz A, Abo-Elenin H.
Role of combination of L-arginine and α- tocopherol in renal transplantation
ischaemia/ reperfusion injury: a randomized controlled experimental study in a rat
model. BJU Int. 2011 Aug;108(4):612-8. doi: 10.1111/j.1464-410X.2010.09943.x.
Epub 2011 May 18
7. Shokeir AA, Hussein AA, Soliman SA, Kamal MM, Abdel-Aziz A, Awadalla A,
Rahim MA, Barakat N. Recoverability of Renal Functions after Relief of Partial
Ureteral Obstruction of Solitary Kidney: Impact of Ferulic Acid. BJU Int. 2012
Sep;110(6):904-11. doi: 10.1111/j.1464-410X.2011.10848.x. Epub 2012 Mar 1.
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8. Hussein AA, El-Dken ZH, Barakat N, Abol-Enein H. Renal ischaemia/reperfusion
injury: possible role of aquaporins. Review article. Acta Physiol (Oxf). 2012
Mar;204(3):308-16. doi: 10.1111/j.1748-1716.2011.02372.x. Epub 2011 Nov 5.
9. Hussein AA, Abdel-Aziz A, Gabr M, Hemmaid KZ. Myocardial and metabolic
dysfunction in type 2 diabetic rats: impact of ghrelin. Can J Physiol Pharmacol. 2012
Jan;90(1):99-111. doi: 10.1139/y11-103. Epub 2011 Dec 21.
10. Hussein AA M., Abbas AM, El Wakil GA, Elsamanoudy AZ, El Aziz AA. Effect of
chronic excess iodine intake on thyroid function and oxidative stress in hypothyroid
rats. Can J Physiol Pharmacol. 2012 May;90(5):617-25. doi: 10.1139/y2012-046.
Epub 2012 May 2.
11. Omar NM, Hussein AM, Malek HA, Saad MA, Saleh DM. Influence of Age on Pain
Sensitivity in Response to Paw Pressure and Formalin Injection in Rats: A Role of
Nitric Oxide. Gen Physiol Biophys. 2012; 31(2):185-94.
12. Mohamed S.H. and Hussein A M.. Altered secretory activity in rat adrenal
chromaffin cells after experimentally induced bronchial asthma and dexamethasone
treatment: ultrastructural and biochemical study. The Egyptian Journal of Histology:
2012; 35 (1): 117–126
13. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Ahmed A. Shokeir.
Systemic and Renal Haemodynamic Changes in Renal Ischemia/Reperfusion Injury:
Impact of Erythropoietin. Can J Physiol Pharmacol. 2012 Nov;90(11):1535-43. doi:
10.1139/y2012-120. Epub 2012 Nov 8.
14. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Ahmed Samy, Azza
Abdelaziz, Sheiri Khater , Nashwa Barakat. Protection against Renal Ischemia/
Reperfusion Injury: A Comparative Experimental Study of the impact of Ischemic
Preconditioning versus Post-conditioning. Arab J of Urology 10 (4): 418-424, 2012.
15. Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza
Abdel-aziz, Ahmed A Shokeir, Ahmed S El-Hefnawy, and Hassan Abol-enein.
Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the
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pathogenesis of bladder cancer. Infect Agent Cancer. 2013 Jun 28;8(1):24. doi:
10.1186/1750-9378-8-24.
16. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Azza Abdelaziz,
Nashwa Barakat. Activation of Nrf2 gene and its dependent genes by ischemic
preconditioning and post-conditioning. Acta Physiol (Oxf). 2013 Sep 7. doi:
10.1111/apha.12164.
17. Samy Eleawa, Hussein F. Sakr, Abdelaziz M. Hussein, Abdullah .S. Assiri,
Mahmoud Alkhateeb, Nervana M. K. Bayoumy. Effect of Testosterone Replacement
Therapy on Cardiac Performance and Oxidative Stress in Orchidecotomized Rats.
Acta Physiol (Oxf). 2013 Oct;209(2):136-47. doi: 10.1111/apha.12158.
18. Sahar Abd Elaziz ELdakroory, Hala Abdel Malek, Abdel-Aziz M. Hussein and
Amira Kamal Elhawary. Evaluation of Doxorubicin Toxicity; Does Ferulic Acid have
a Possible Protective Effect like Ginkgobiloba? Mansoura Journal of Forensic
Medicine and Clinical Toxicology, Jan, 2013.
19. Abd El-Aziz M. Hussein, Aya Abd-Elkhabir, Amany Abozahra, Azza Baiomy,
Sylvia A. Ashamallah, Hussein A. Sheashaa, Mohamed A. Sobh. Pancreatic Injury
Secondary to Renal Ischemia/Reperfusion (I/R) Injury: Possible Role of Oxidative
Stress. Physiol Res. 2014;63(1):47-55. Epub 2013 Nov 1.
20. Abd El-Aziz M Hussein, Mohamed O Seisa, Hazem K Khaled, , Mie M Ali , Amel
A Ezzat, Azza Baiomy, Hussein A Sheashaa, Mohamed A Sobh. Hepatic injury
induced by ischemia/reperfusion role: role of nitric oxide. General physiology and
biophysics. 2014;33(2):205-13. doi: 10.4149/gpb_2013084.
21. Mohammed E. Sarhan, Hanaa G. El-Serougy, Abdelaziz M. Hussein, Mohamed El-
dosoky, Mohammed A. Sobh, Fatma Elhusseini. Impact of Bone Marrow-Derived
Mesenchymal Stem Cells on Adriamycin-Induced Chronic Nephropathy. Can J
Physiol Pharmacol. 2014 Sep;92(9):733-43. doi: 10.1139/cjpp-2013-0503. Epub 2014
Apr 8
22. Sakr HF1, Khalil KI, Hussein AM, Zaki MS, Eid RA, Alkhateeb M. Effect of
Dehydroepiandrosterone (DHEA) on Memory and Brain derived neurotrophic factor
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(BDNF) in a Rat Model of Vascular Dementia. J Physiol Pharmacol. 2014 Feb;
65(1):41-53.
23. Kamel Zaki Hemmaid, Amira Awadalla, Hassan Aboelenin, Abdelaziz M. Hussein,
Essam Elsawy, Mai B Mohammed, Abd El-Rahman, Nabawy Zekri Microsatellite
Chromosomal Instability in Bladder Cancer Patients Infected with Hepatitis C Virus.
IJSR – inter J Scientific Research, 2014; 3(9): 2277 - 8179
24. Ahmed A. Shokeir Amira Awadalla, Hassan Aboelenin, Kamel Zaki Hemmaid,
Abdelaziz M. Hussein, Essam Elsawy, Rania A. Nada , Azza Abdelaziz. Pattern of
DNA Hypermethylation of APC, P16, P73, P16, O6MMGT, CD99 and CDH1 Genes
in Bladder Cancer with Hepatitis C Viral (HCV) Infection. Inter J of Cancer
Research, 2015,49(1): 1690-1703
25. Abdelaziz M Hussein, Amani MD El-Mousalamy, Sahar AM Hussein, Seham A
Mahmoud. Effects of Palm Dates (Phoenix Dactylifera L) Extracts on Hepatic
Dysfunctions in Type 2 Diabetic Rat Model. World J Pharmacy and Pharmaceutical
Sciences. 4(7): 62-79: 2015
26. Ahmed A. Shokeir, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla,
Ahmed Harraz, Shery Khater, Kamel Hemmaid. Activation of Nrf2 by Ischemic
Preconditioning and Sulforaphane in Renal Ischemia/Reperfusion Injury: A
Comparative Experimental Study. Physiol Res. 2015;64(3):313-23.
27. Mohamed Zahran, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla,
Ahmed Harraz, Shery Khater, Ahmed A. Shokeir. Sildenafil activates antioxidant and
antiapoptotic genes and inhibits proinflammatory cytokine genes in a rat model of
renal ischemia/reperfusion injury. Int J Urol Nehrol 2015, 47(11): 1907-1915
28. Ahmed A. Shokeir, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla,
Ahmed Harraz, Shery Khater, Kamel Hemmaid. Remote limb ischemic
preconditioning (rIPC) activates antioxidant and antiapoptotic genes and inhibit
proinflammatory cytokine genes in renal ischemia/reperfusion injury. Gen Physiol
Biophys. 2015 Nov 27.
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29. Abdelaziz M. Hussein, Mohamed El-dosoky, Ahmed Handle, Mohammed E.
Sarhan, Hanaa G. El-Serougy, Mohammed A. Sobh, Mahmoud Elhussiny, Eman El
Nashar. Effects of alpha darbopeiotin on Adriamycin-Induced Chronic Nephropathy.
Accepted in Int J urol Nephrol 2015
30. Hassan Abol-Enein, Abdelrhaman N. Zekri, Abdel-aziz M. Hussein, Amira
Awadalla, Amira ALHawari, Sherry Khater, Kamel Z. Hemmaid, Mai Bakr, Ahmed
A. Shokeir. Molecular Profiling of Early Stage Bilharzial Bladder Cancer in Egypt by
cDNA Microarray. Inter J of Cancer Research, 2015,article in press.
31. Abdelaziz M. Hussein, Hala Abdel Malek and Mohamed Ahdy Saad. Renoprotective
Effects Aliskiren on Adenine-induced Tubulointerstitial Nephropathy: Possible
Underlying Mechanisms. Accepted in Canad. J. Physiol. Pharmacol. 2016
32. El-Hussainy M.A. El-Hussainy, Abdelaziz M. Hussein, Azza Abdelaziz, Ibrahim El-
Mehasseb. Effects of Aluminum oxide (Al O ) Nanoparticles on ECG, Myocardial
2 3
Inflammatory Cytokines, Redox State and Connexin 43 and Lipid Profile in Rats:
Possible Cardioprotective Effect of Gallic Acid. Accepted in Canad. J. Physiol.
Pharmacol. 2016.
33. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Mahmoud M. Gabr,
Sherry Khater, Ahmed Harraz, Ahmed A. Shokeir. Modulation of Renal
Ischemia/Reperfusion in Rats by A Combination Ischemic Preconditioning and
Adipose-Derived Mesenchymal Stem Cells (ADMSCs). Accepted in Canad. J.
Physiol. Pharmacol. 2016.
34. Amani M.D. El-Mousalamy, Abdelaziz M. Hussein, Seham A. Mahmoud, Azza
Abdelaziz, Gehan Shaker. Aqueous and Methanolic Extracts of Palm Date Seed and
Fruit Flesh (Phoenix Dactylifera) Protects Against Diabetic Nephropathy in Type II
Diabetic Rats. J Biochemistry and Physiology: Open Access, Accepted 2016.
35. Hussein AM, Ghalwash M, Magdy K, Abulseoud OA.Beta Lactams Antibiotic
Ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43 Expression in
Hippocampus of Pentylenetetrazole Kindled Rats. J Epilepsy Res. 2016 30;6(1):8-15.
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